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LearnPAB2472
antibody from Abnova Corporation
Targeting: APOBEC3G
bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB2472 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2472, RRID:AB_1571267
- Product name
- APOBEC3G polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of APOBEC3G.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity.
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.
Stopak K, de Noronha C, Yonemoto W, Greene WC
Molecular cell 2003 Sep;12(3):591-601
Molecular cell 2003 Sep;12(3):591-601
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity.
Kao S, Khan MA, Miyagi E, Plishka R, Buckler-White A, Strebel K
Journal of virology 2003 Nov;77(21):11398-407
Journal of virology 2003 Nov;77(21):11398-407
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.
Mangeat B, Turelli P, Caron G, Friedli M, Perrin L, Trono D
Nature 2003 Jul 3;424(6944):99-103
Nature 2003 Jul 3;424(6944):99-103
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The APOBEC3G polyclonal antibody (Cat # PAB2472) is used in Western blot to detect APOBEC3G in A-375 cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the APOBEC3G polyclonal antibody (Cat # PAB2472) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
