ABIN357439

antibody from antibodies-online

Targeting: SOX2

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN357439

Provider

antibodies-online

Product name

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody

Antibody type

Polyclonal

Description

Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Reactivity

Human

Host

Rabbit

Vial size

0.4 mL

Storage

Store the antibody at 2 - 8°C up to one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity.

Wiebe MS, Nowling TK, Rizzino A
The Journal of biological chemistry 2003 May 16;278(20):17901-11

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Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.

Reményi A, Lins K, Nissen LJ, Reinbold R, Schöler HR, Wilmanns M
Genes & development 2003 Aug 15;17(16):2048-59

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Mutations in SOX2 cause anophthalmia.

Fantes J, Ragge NK, Lynch SA, McGill NI, Collin JR, Howard-Peebles PN, Hayward C, Vivian AJ, Williamson K, van Heyningen V, FitzPatrick DR
Nature genetics 2003 Apr;33(4):461-3

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Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.

Schepers GE, Teasdale RD, Koopman P
Developmental cell 2002 Aug;3(2):167-70

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Pairing SOX off: with partners in the regulation of embryonic development.

Kamachi Y, Uchikawa M, Kondoh H
Trends in genetics : TIG 2000 Apr;16(4):182-7