NBP2-47857B

antibody from Novus Biologicals

Targeting: AR AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

NBP2-47857B

Provider

Novus Biologicals

Product name

Mouse Monoclonal Androgen R/NR3C4 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Biotin

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.