NBP2-34515AF700

antibody from Novus Biologicals
Targeting: BCL2 Bcl-2, PPP1R50
Provider product page for NBP2-34515AF700
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-34515AF700 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Bcl-2 Antibody
Antibody type
Monoclonal
Description
Protein A purified. This antibody recognizes a protein of 25-26kDa, identified as the bcl-2 alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Near infrared dye
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C in the dark.
BCL2 protein structure - NBP2-34515AF700 shown in red.