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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [29]
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- Product number
- GTX41836 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX41836, RRID:AB_11162813
- Product name
- CD8 alpha antibody [53-6.7]
- Antibody type
- Monoclonal
- Reactivity
- Mouse
- Host
- Rat
Submitted references Dickkopf-3 Contributes to the Regulation of Anti-Tumor Immune Responses by Mesenchymal Stem Cells.
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Skeletal muscle atrophy is attenuated in tumor-bearing mice under chemotherapy by treatment with fish oil and selenium.
α-Galactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3.
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
Reduction of splenic immunosuppressive cells and enhancement of anti-tumor immunity by synergy of fish oil and selenium yeast.
CD8+ T cell-induced expression of tissue inhibitor of metalloproteinses-1 exacerbated osteoarthritis.
Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice.
Anti-CCL25 antibody prolongs skin allograft survival by blocking CCR9 expression and impairing splenic T-cell function.
Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells.
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
Flt3L-mobilized dendritic cells bearing H2-Kbm1 apoptotic cells do not induce cross-tolerance to CD8+ T cells across a class I MHC mismatched barrier.
Arachidonate 5-lipoxygenase establishes adaptive humoral immunity by controlling primary B cells and their cognate T-cell help.
Effects of TCDD on the fate of naive dendritic cells.
IFN-gamma inhibits IL-4-induced type 2 cytokine expression by CD8 T cells in vivo and modulates the anti-tumor response.
Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development.
Elimination of immunodominant epitopes from multispecific DNA-based vaccines allows induction of CD8 T cells that have a striking antiviral potential.
Tumor-localized ligation of CD3 and CD28 with systemic regulatory T-cell depletion induces potent innate and adaptive antitumor responses.
Loss of protein kinase C theta, Bcl10, or Malt1 selectively impairs proliferation and NF-kappa B activation in the CD4+ T cell subset.
The early kinetics of cytomegalovirus-specific CD8+ T-cell responses are not affected by antigen load or the absence of perforin or gamma interferon.
Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses.
Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo.
CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses.
The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses.
Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification.
Mac-1+ cells are the predominant subset in the early hepatic lesions of mice infected with Francisella tularensis.
alpha-Galactosylceramide can act as a nasal vaccine adjuvant inducing protective immune responses against viral infection and tumor.
Loss of CD8 and TCR binding to Class I MHC ligands following T cell activation.
Lu KH, Tounsi A, Shridhar N, Küblbeck G, Klevenz A, Prokosch S, Bald T, Tüting T, Arnold B
Frontiers in immunology 2015 Dec 24;6:645
Frontiers in immunology 2015 Dec 24;6:645
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Laidlaw BJ, Cui W, Amezquita RA, Gray SM, Guan T, Lu Y, Kobayashi Y, Flavell RA, Kleinstein SH, Craft J, Kaech SM
Nature immunology 2015 Aug;16(8):871-9
Nature immunology 2015 Aug;16(8):871-9
Skeletal muscle atrophy is attenuated in tumor-bearing mice under chemotherapy by treatment with fish oil and selenium.
Wang H, Li TL, Hsia S, Su IL, Chan YL, Wu CJ
Oncotarget 2015 Apr 10;6(10):7758-73
Oncotarget 2015 Apr 10;6(10):7758-73
α-Galactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3.
Huang JR, Tsai YC, Chang YJ, Wu JC, Hung JT, Lin KH, Wong CH, Yu AL
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 15;192(4):1972-81
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 15;192(4):1972-81
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
Eitas TK, Chou WC, Wen H, Gris D, Robbins GR, Brickey J, Oyama Y, Ting JP
The Journal of biological chemistry 2014 Feb 14;289(7):4173-9
The Journal of biological chemistry 2014 Feb 14;289(7):4173-9
Reduction of splenic immunosuppressive cells and enhancement of anti-tumor immunity by synergy of fish oil and selenium yeast.
Wang H, Chan YL, Li TL, Bauer BA, Hsia S, Wang CH, Huang JS, Wang HM, Yeh KY, Huang TH, Wu GJ, Wu CJ
PloS one 2013;8(1):e52912
PloS one 2013;8(1):e52912
CD8+ T cell-induced expression of tissue inhibitor of metalloproteinses-1 exacerbated osteoarthritis.
Hsieh JL, Shiau AL, Lee CH, Yang SJ, Lee BO, Jou IM, Wu CL, Chen SH, Shen PC
International journal of molecular sciences 2013 Oct 8;14(10):19951-70
International journal of molecular sciences 2013 Oct 8;14(10):19951-70
Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice.
Kastenmüller K, Espinosa DA, Trager L, Stoyanov C, Salazar AM, Pokalwar S, Singh S, Dutta S, Ockenhouse CF, Zavala F, Seder RA
Infection and immunity 2013 Mar;81(3):789-800
Infection and immunity 2013 Mar;81(3):789-800
Anti-CCL25 antibody prolongs skin allograft survival by blocking CCR9 expression and impairing splenic T-cell function.
Li J, Xiong T, Xiao R, Xiong A, Chen J, Altaf E, Zheng Y, Zhu G, He Y, Tan J
Archivum immunologiae et therapiae experimentalis 2013 Jun;61(3):237-44
Archivum immunologiae et therapiae experimentalis 2013 Jun;61(3):237-44
Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells.
Spranger S, Spaapen RM, Zha Y, Williams J, Meng Y, Ha TT, Gajewski TF
Science translational medicine 2013 Aug 28;5(200):200ra116
Science translational medicine 2013 Aug 28;5(200):200ra116
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
Gong Y, Wang Z, Liang Z, Duan H, Ouyang L, Yu Q, Xu Z, Shen G, Weng X, Wu X
PloS one 2012;7(10):e47435
PloS one 2012;7(10):e47435
Flt3L-mobilized dendritic cells bearing H2-Kbm1 apoptotic cells do not induce cross-tolerance to CD8+ T cells across a class I MHC mismatched barrier.
del Rio ML, Cote-Sierra J, Rodriguez-Barbosa JI
Transplant international : official journal of the European Society for Organ Transplantation 2011 May;24(5):501-13
Transplant international : official journal of the European Society for Organ Transplantation 2011 May;24(5):501-13
Arachidonate 5-lipoxygenase establishes adaptive humoral immunity by controlling primary B cells and their cognate T-cell help.
Nagashima T, Ichimiya S, Kikuchi T, Saito Y, Matsumiya H, Ara S, Koshiba S, Zhang J, Hatate C, Tonooka A, Kubo T, Ye RC, Hirose B, Shirasaki H, Izumi T, Takami T, Himi T, Sato N
The American journal of pathology 2011 Jan;178(1):222-32
The American journal of pathology 2011 Jan;178(1):222-32
Effects of TCDD on the fate of naive dendritic cells.
Bankoti J, Burnett A, Navarro S, Miller AK, Rase B, Shepherd DM
Toxicological sciences : an official journal of the Society of Toxicology 2010 Jun;115(2):422-34
Toxicological sciences : an official journal of the Society of Toxicology 2010 Jun;115(2):422-34
IFN-gamma inhibits IL-4-induced type 2 cytokine expression by CD8 T cells in vivo and modulates the anti-tumor response.
Apte SH, Groves P, Olver S, Baz A, Doolan DL, Kelso A, Kienzle N
Journal of immunology (Baltimore, Md. : 1950) 2010 Jul 15;185(2):998-1004
Journal of immunology (Baltimore, Md. : 1950) 2010 Jul 15;185(2):998-1004
Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
Medyouf H, Gao X, Armstrong F, Gusscott S, Liu Q, Gedman AL, Matherly LH, Schultz KR, Pflumio F, You MJ, Weng AP
Blood 2010 Feb 11;115(6):1175-84
Blood 2010 Feb 11;115(6):1175-84
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development.
Todd DJ, McHeyzer-Williams LJ, Kowal C, Lee AH, Volpe BT, Diamond B, McHeyzer-Williams MG, Glimcher LH
The Journal of experimental medicine 2009 Sep 28;206(10):2151-9
The Journal of experimental medicine 2009 Sep 28;206(10):2151-9
Elimination of immunodominant epitopes from multispecific DNA-based vaccines allows induction of CD8 T cells that have a striking antiviral potential.
Riedl P, Wieland A, Lamberth K, Buus S, Lemonnier F, Reifenberg K, Reimann J, Schirmbeck R
Journal of immunology (Baltimore, Md. : 1950) 2009 Jul 1;183(1):370-80
Journal of immunology (Baltimore, Md. : 1950) 2009 Jul 1;183(1):370-80
Tumor-localized ligation of CD3 and CD28 with systemic regulatory T-cell depletion induces potent innate and adaptive antitumor responses.
Lee CH, Chiang YH, Chang SE, Chong CL, Cheng BM, Roffler SR
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Apr 15;15(8):2756-66
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Apr 15;15(8):2756-66
Loss of protein kinase C theta, Bcl10, or Malt1 selectively impairs proliferation and NF-kappa B activation in the CD4+ T cell subset.
Kingeter LM, Schaefer BC
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6244-54
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6244-54
The early kinetics of cytomegalovirus-specific CD8+ T-cell responses are not affected by antigen load or the absence of perforin or gamma interferon.
Andrews DM, Andoniou CE, Fleming P, Smyth MJ, Degli-Esposti MA
Journal of virology 2008 May;82(10):4931-7
Journal of virology 2008 May;82(10):4931-7
Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses.
Kenna TJ, Thomas R, Steptoe RJ
Blood 2008 Feb 15;111(4):2091-100
Blood 2008 Feb 15;111(4):2091-100
Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo.
Britschgi MR, Link A, Lissandrin TK, Luther SA
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):7681-8
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):7681-8
CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses.
Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, van Rooijen N, Hovav AH, Letvin NL
Blood 2008 Dec 1;112(12):4585-90
Blood 2008 Dec 1;112(12):4585-90
The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses.
Jordan JM, Woods ME, Olano J, Walker DH
Infection and immunity 2008 Aug;76(8):3717-24
Infection and immunity 2008 Aug;76(8):3717-24
Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification.
Guo Y, Maillard I, Chakraborti S, Rothenberg EV, Speck NA
Blood 2008 Aug 1;112(3):480-92
Blood 2008 Aug 1;112(3):480-92
Mac-1+ cells are the predominant subset in the early hepatic lesions of mice infected with Francisella tularensis.
Rasmussen JW, Cello J, Gil H, Forestal CA, Furie MB, Thanassi DG, Benach JL
Infection and immunity 2006 Dec;74(12):6590-8
Infection and immunity 2006 Dec;74(12):6590-8
alpha-Galactosylceramide can act as a nasal vaccine adjuvant inducing protective immune responses against viral infection and tumor.
Ko SY, Ko HJ, Chang WS, Park SH, Kweon MN, Kang CY
Journal of immunology (Baltimore, Md. : 1950) 2005 Sep 1;175(5):3309-17
Journal of immunology (Baltimore, Md. : 1950) 2005 Sep 1;175(5):3309-17
Loss of CD8 and TCR binding to Class I MHC ligands following T cell activation.
Kao C, Daniels MA, Jameson SC
International immunology 2005 Dec;17(12):1607-17
International immunology 2005 Dec;17(12):1607-17
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