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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- MAB4385 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB4385, RRID:AB_10629136
- Product name
- MS4A1 monoclonal antibody, clone LT20 (FITC)
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against native MS4A1.
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- LT20
- Storage
- Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Submitted references The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.
CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts.
Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.
Teeling JL, Mackus WJ, Wiegman LJ, van den Brakel JH, Beers SA, French RR, van Meerten T, Ebeling S, Vink T, Slootstra JW, Parren PW, Glennie MJ, van de Winkel JG
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 1;177(1):362-71
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 1;177(1):362-71
CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts.
Chan HT, Hughes D, French RR, Tutt AL, Walshe CA, Teeling JL, Glennie MJ, Cragg MS
Cancer research 2003 Sep 1;63(17):5480-9
Cancer research 2003 Sep 1;63(17):5480-9
Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.
Polyak MJ, Deans JP
Blood 2002 May 1;99(9):3256-62
Blood 2002 May 1;99(9):3256-62
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Surface staining of human peripheral blood cells with MS4A1 monoclonal antibody, clone LT20 (FITC) (Cat # MAB4385).
- Validation comment
- Flow Cytometry
