ABIN362047

antibody from antibodies-online

Targeting: TP53 LFS1, p53

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN362047

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN362047, RRID:AB_10956437

Product name

anti-Tumor Protein P53 (TP53) (pThr18) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pThr18 (Q-E-T (p) -F-S) derived from Human p53. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human

Host

Rabbit

Epitope

pThr18

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression.

Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, Appella E, Xu Y
Nature cell biology 2005 Feb;7(2):165-71

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ATM-dependent CHK2 activation induced by anticancer agent, irofulven.

Wang J, Wiltshire T, Wang Y, Mikell C, Burks J, Cunningham C, Van Laar ES, Waters SJ, Reed E, Wang W
The Journal of biological chemistry 2004 Sep 17;279(38):39584-92

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Hypoxia-induced nucleophosmin protects cell death through inhibition of p53.

Li J, Zhang X, Sejas DP, Bagby GC, Pang Q
The Journal of biological chemistry 2004 Oct 1;279(40):41275-9

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p53 Stabilization and accumulation induced by human vaccinia-related kinase 1.

Vega FM, Sevilla A, Lazo PA
Molecular and cellular biology 2004 Dec;24(23):10366-80