ABIN362450

antibody from antibodies-online

Targeting: TP53 LFS1, p53

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362450

Provider

antibodies-online

Product name

anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (pSer1232) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer1232 (P-V-S (p) -P-L) derived from Human eIF4G. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human

Host

Rabbit

Epitope

pSer1232

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Translational activation of uncapped mRNAs by the central part of human eIF4G is 5' end-dependent.

De Gregorio E, Preiss T, Hentze MW
RNA (New York, N.Y.) 1998 Jul;4(7):828-36

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A novel functional human eukaryotic translation initiation factor 4G.

Gradi A, Imataka H, Svitkin YV, Rom E, Raught B, Morino S, Sonenberg N
Molecular and cellular biology 1998 Jan;18(1):334-42

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Intact eukaryotic initiation factor 4G is required for hepatitis A virus internal initiation of translation.

Borman AM, Kean KM
Virology 1997 Oct 13;237(1):129-36

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Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator.

Piirsoo M, Ustav E, Mandel T, Stenlund A, Ustav M
The EMBO journal 1996 Jan 2;15(1):1-11