PA2232

antibody from Boster Biological Technology
Targeting: AIFM1 AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8
Provider product page for PA2232
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
PA2232 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-AIF/AIFM1 Antibody
Antibody type
Polyclonal
Description
Polyclonal antibody for AIF/AIFM1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. AIF/AIFM1 information: Molecular Weight: 66901 MW; Subcellular Localization: Mitochondrion intermembrane space. Mitochondrion inner membrane. Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Proteolytic cleavage during or just after translocation into the mitochondrial intermembrane space (IMS) results in the formation of an inner-membrane-anchored mature form (AIFmit). During apoptosis, further proteolytic processing leads to a mature form, which is confined to the mitochondrial IMS in a soluble form (AIFsol). AIFsol is released to the cytoplasm in response to specific death signals, and translocated to the nucleus, where it induces nuclear apoptosis. Colocalizes with EIF3G in the nucleus and perinuclear region; Tissue Specificity: Detected in muscle and skin fibroblasts (at protein level). Isoform 5 is frequently down-regulated in human cancers.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Vial size
100μg/vial
Concentration
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Handling
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
AIFM1 protein structure - PA2232 shown in red.