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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN361930 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Activating Transcription Factor 2 (ATF2) (pSer62), (pSer44) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer62 or 44 (N-D-S (p) -V-I) derived from Human ATF2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer62,pSer44
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK.
Transcription factor ATF2 regulation by the JNK signal transduction pathway.
ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.
Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases.
Phosphorylation of cAMP response element-binding protein, CRE-BP1, by cAMP-dependent protein kinase and protein kinase C.
Sevilla A, Santos CR, Vega FM, Lazo PA
The Journal of biological chemistry 2004 Jun 25;279(26):27458-65
The Journal of biological chemistry 2004 Jun 25;279(26):27458-65
Transcription factor ATF2 regulation by the JNK signal transduction pathway.
Gupta S, Campbell D, Dérijard B, Davis RJ
Science (New York, N.Y.) 1995 Jan 20;267(5196):389-93
Science (New York, N.Y.) 1995 Jan 20;267(5196):389-93
ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.
van Dam H, Wilhelm D, Herr I, Steffen A, Herrlich P, Angel P
The EMBO journal 1995 Apr 18;14(8):1798-811
The EMBO journal 1995 Apr 18;14(8):1798-811
Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases.
Abdel-Hafiz HA, Heasley LE, Kyriakis JM, Avruch J, Kroll DJ, Johnson GL, Hoeffler JP
Molecular endocrinology (Baltimore, Md.) 1992 Dec;6(12):2079-89
Molecular endocrinology (Baltimore, Md.) 1992 Dec;6(12):2079-89
Phosphorylation of cAMP response element-binding protein, CRE-BP1, by cAMP-dependent protein kinase and protein kinase C.
Sakurai A, Maekawa T, Sudo T, Ishii S, Kishimoto A
Biochemical and biophysical research communications 1991 Dec 16;181(2):629-35
Biochemical and biophysical research communications 1991 Dec 16;181(2):629-35
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