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- Antibody Data
- Antigen structure
- References [54]
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- Validations
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- Product number
- FAB197F-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CCR7 Fluorescein-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CCR7.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAA58615- Isotype
- IgG
- Antibody clone number
- 150503
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Cancer Immunotherapy with T Cells Carrying Bispecific Receptors That Mimic Antibodies.
TCR activation mimics CD127lowPD-1high phenotype and functional alterations of T lymphocytes from septic shock patients.
Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts.
Age-related differences in humoral and cellular immune responses after primary immunisation: indications for stratified vaccination schedules.
Innate and adaptive immune dysregulation in critically ill ICU patients.
pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients.
PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer.
NKG2D Ligand-Targeted Bispecific T-Cell Engagers Lead to Robust Antitumor Activity against Diverse Human Tumors.
Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study.
Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides.
Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study.
Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity.
Tumor-infiltrating Tim-3+ T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk.
Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells.
Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.
Glycolysis determines dichotomous regulation of T cell subsets in hypoxia.
Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways.
Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo.
STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function.
Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.
Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+ T cells in chronic infection.
CD40L induces functional tunneling nanotube networks exclusively in dendritic cells programmed by mediators of type 1 immunity.
Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.
Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen.
IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential.
Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation.
Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders.
Severe acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses.
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Both HLA-B*57 and plasma HIV RNA levels contribute to the HIV-specific CD8+ T cell response in HIV controllers.
Peripheral blood CD56(bright) NK cells respond to stem cell factor and adhere to its membrane-bound form after upregulation of c-kit.
Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango.
TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys.
MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial.
Bone marrow T cells from the femur are similar to iliac crest derived cells in old age and represent a useful tool for studying the aged immune system.
CCR5 is a receptor for Staphylococcus aureus leukotoxin ED.
CCR2(+)CCR5(+) T cells produce matrix metalloproteinase-9 and osteopontin in the pathogenesis of multiple sclerosis.
Biomarkers on melanoma patient T cells associated with ipilimumab treatment.
The CD46-Jagged1 interaction is critical for human TH1 immunity.
Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation.
Identification of human NK17/NK1 cells.
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response.
CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia.
Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells.
Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.
Intravenous immunoglobulins suppress T-cell priming by modulating the bidirectional interaction between dendritic cells and natural killer cells.
Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.
Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection.
Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
Ahn S, Li J, Sun C, Gao K, Hirabayashi K, Li H, Savoldo B, Liu R, Dotti G
Cancer immunology research 2019 May;7(5):773-783
Cancer immunology research 2019 May;7(5):773-783
TCR activation mimics CD127lowPD-1high phenotype and functional alterations of T lymphocytes from septic shock patients.
Mouillaux J, Allam C, Gossez M, Uberti T, Delwarde B, Hayman J, Rimmelé T, Textoris J, Monneret G, Peronnet E, Venet F
Critical care (London, England) 2019 Apr 17;23(1):131
Critical care (London, England) 2019 Apr 17;23(1):131
Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts.
Gary R, Aigner M, Moi S, Schaffer S, Gottmann A, Maas S, Zimmermann R, Zingsem J, Strobel J, Mackensen A, Mautner J, Moosmann A, Gerbitz A
Journal of translational medicine 2018 May 9;16(1):124
Journal of translational medicine 2018 May 9;16(1):124
Age-related differences in humoral and cellular immune responses after primary immunisation: indications for stratified vaccination schedules.
Wagner A, Garner-Spitzer E, Jasinska J, Kollaritsch H, Stiasny K, Kundi M, Wiedermann U
Scientific reports 2018 Jun 29;8(1):9825
Scientific reports 2018 Jun 29;8(1):9825
Innate and adaptive immune dysregulation in critically ill ICU patients.
Duggal NA, Snelson C, Shaheen U, Pearce V, Lord JM
Scientific reports 2018 Jul 5;8(1):10186
Scientific reports 2018 Jul 5;8(1):10186
pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients.
Huang L, Litjens NHR, Kannegieter NM, Klepper M, Baan CC, Betjes MGH
Immunity & ageing : I & A 2017;14:14
Immunity & ageing : I & A 2017;14:14
PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer.
Kansy BA, Concha-Benavente F, Srivastava RM, Jie HB, Shayan G, Lei Y, Moskovitz J, Moy J, Li J, Brandau S, Lang S, Schmitt NC, Freeman GJ, Gooding WE, Clump DA, Ferris RL
Cancer research 2017 Nov 15;77(22):6353-6364
Cancer research 2017 Nov 15;77(22):6353-6364
NKG2D Ligand-Targeted Bispecific T-Cell Engagers Lead to Robust Antitumor Activity against Diverse Human Tumors.
Godbersen C, Coupet TA, Huehls AM, Zhang T, Battles MB, Fisher JL, Ernstoff MS, Sentman CL
Molecular cancer therapeutics 2017 Jul;16(7):1335-1346
Molecular cancer therapeutics 2017 Jul;16(7):1335-1346
Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study.
Hazeldine J, Naumann DN, Toman E, Davies D, Bishop JRB, Su Z, Hampson P, Dinsdale RJ, Crombie N, Duggal NA, Harrison P, Belli A, Lord JM
PLoS medicine 2017 Jul;14(7):e1002338
PLoS medicine 2017 Jul;14(7):e1002338
Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides.
Stenberg L, Stößel M, Ronchi G, Geuna S, Yin Y, Mommert S, Mårtensson L, Metzen J, Grothe C, Dahlin LB, Haastert-Talini K
BMC neuroscience 2017 Jul 18;18(1):53
BMC neuroscience 2017 Jul 18;18(1):53
Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
Gavegnano C, Brehm JH, Dupuy FP, Talla A, Ribeiro SP, Kulpa DA, Cameron C, Santos S, Hurwitz SJ, Marconi VC, Routy JP, Sabbagh L, Schinazi RF, Sékaly RP
PLoS pathogens 2017 Dec;13(12):e1006740
PLoS pathogens 2017 Dec;13(12):e1006740
Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study.
Rea D, Henry G, Khaznadar Z, Etienne G, Guilhot F, Nicolini F, Guilhot J, Rousselot P, Huguet F, Legros L, Gardembas M, Dubruille V, Guerci-Bresler A, Charbonnier A, Maloisel F, Ianotto JC, Villemagne B, Mahon FX, Moins-Teisserenc H, Dulphy N, Toubert A
Haematologica 2017 Aug;102(8):1368-1377
Haematologica 2017 Aug;102(8):1368-1377
Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity.
Maghazachi AA, Sand KL, Al-Jaderi Z
Frontiers in immunology 2016;7:437
Frontiers in immunology 2016;7:437
Tumor-infiltrating Tim-3+ T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk.
Li J, Shayan G, Avery L, Jie HB, Gildener-Leapman N, Schmitt N, Lu BF, Kane LP, Ferris RL
Oncoimmunology 2016;5(10):e1200778
Oncoimmunology 2016;5(10):e1200778
Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells.
Smith KN, Mailliard RB, Piazza PA, Fischer W, Korber BT, Fecek RJ, Ratner D, Gupta P, Mullins JI, Rinaldo CR
mBio 2016 May 31;7(3)
mBio 2016 May 31;7(3)
Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.
Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, Gardner M, Lewis MG, Hatziioannou T, Santra S, Apetrei C, Pandrea I, Alam SM, Liao HX, Shen X, Tomaras GD, Farzan M, Chertova E, Keele BF, Estes JD, Lifson JD, Doms RW, Montefiori DC, Haynes BF, Sodroski JG, Kwong PD, Hahn BH, Shaw GM
Proceedings of the National Academy of Sciences of the United States of America 2016 Jun 14;113(24):E3413-22
Proceedings of the National Academy of Sciences of the United States of America 2016 Jun 14;113(24):E3413-22
Glycolysis determines dichotomous regulation of T cell subsets in hypoxia.
Xu Y, Chaudhury A, Zhang M, Savoldo B, Metelitsa LS, Rodgers J, Yustein JT, Neilson JR, Dotti G
The Journal of clinical investigation 2016 Jul 1;126(7):2678-88
The Journal of clinical investigation 2016 Jul 1;126(7):2678-88
Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways.
Hudspeth K, Donadon M, Cimino M, Pontarini E, Tentorio P, Preti M, Hong M, Bertoletti A, Bicciato S, Invernizzi P, Lugli E, Torzilli G, Gershwin ME, Mavilio D
Journal of autoimmunity 2016 Jan;66:40-50
Journal of autoimmunity 2016 Jan;66:40-50
Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo.
Costa M, Cruz E, Oliveira S, Benes V, Ivacevic T, Silva MJ, Vieira I, Dias F, Fonseca S, Gonçalves M, Lima M, Leitão C, Muckenthaler MU, Pinto J, Porto G
PloS one 2015;10(4):e0124246
PloS one 2015;10(4):e0124246
STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function.
Wilson RP, Ives ML, Rao G, Lau A, Payne K, Kobayashi M, Arkwright PD, Peake J, Wong M, Adelstein S, Smart JM, French MA, Fulcher DA, Picard C, Bustamante J, Boisson-Dupuis S, Gray P, Stepensky P, Warnatz K, Freeman AF, Rossjohn J, McCluskey J, Holland SM, Casanova JL, Uzel G, Ma CS, Tangye SG, Deenick EK
The Journal of experimental medicine 2015 Jun 1;212(6):855-64
The Journal of experimental medicine 2015 Jun 1;212(6):855-64
Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.
Thomas S, Klobuch S, Podlech J, Plachter B, Hoffmann P, Renzaho A, Theobald M, Reddehase MJ, Herr W, Lemmermann NA
PLoS pathogens 2015 Jul;11(7):e1005049
PLoS pathogens 2015 Jul;11(7):e1005049
Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+ T cells in chronic infection.
Nitschke K, Flecken T, Schmidt J, Gostick E, Marget M, Neumann-Haefelin C, Blum HE, Price DA, Thimme R
Journal of virology 2015 Jan;89(1):25-34
Journal of virology 2015 Jan;89(1):25-34
CD40L induces functional tunneling nanotube networks exclusively in dendritic cells programmed by mediators of type 1 immunity.
Zaccard CR, Watkins SC, Kalinski P, Fecek RJ, Yates AL, Salter RD, Ayyavoo V, Rinaldo CR, Mailliard RB
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 1;194(3):1047-56
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 1;194(3):1047-56
Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.
Santra S, Tomaras GD, Warrier R, Nicely NI, Liao HX, Pollara J, Liu P, Alam SM, Zhang R, Cocklin SL, Shen X, Duffy R, Xia SM, Schutte RJ, Pemble Iv CW, Dennison SM, Li H, Chao A, Vidnovic K, Evans A, Klein K, Kumar A, Robinson J, Landucci G, Forthal DN, Montefiori DC, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Rerks-Ngarm S, Robb ML, Michael NL, Kim JH, Soderberg KA, Giorgi EE, Blair L, Korber BT, Moog C, Shattock RJ, Letvin NL, Schmitz JE, Moody MA, Gao F, Ferrari G, Shaw GM, Haynes BF
PLoS pathogens 2015 Aug;11(8):e1005042
PLoS pathogens 2015 Aug;11(8):e1005042
Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen.
de Mare-Bredemeijer EL, Shi XL, Mancham S, van Gent R, van der Heide-Mulder M, de Boer R, Heemskerk MH, de Jonge J, van der Laan LJ, Metselaar HJ, Kwekkeboom J
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1838-48
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1838-48
IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential.
Lehmann D, Spanholtz J, Sturtzel C, Tordoir M, Schlechta B, Groenewegen D, Hofer E
PloS one 2014;9(1):e87131
PloS one 2014;9(1):e87131
Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation.
Killig M, Friedrichs B, Meisig J, Gentilini C, Blüthgen N, Loddenkemper C, Labopin M, Basara N, Pfrepper C, Niederwieser DW, Uharek L, Romagnani C
European journal of immunology 2014 Sep;44(9):2822-34
European journal of immunology 2014 Sep;44(9):2822-34
Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders.
Perreau M, Vigano S, Bellanger F, Pellaton C, Buss G, Comte D, Roger T, Lacabaratz C, Bart PA, Levy Y, Pantaleo G
The Journal of experimental medicine 2014 Sep 22;211(10):2033-45
The Journal of experimental medicine 2014 Sep 22;211(10):2033-45
Severe acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses.
Clay CC, Donart N, Fomukong N, Knight JB, Overheim K, Tipper J, Van Westrienen J, Hahn F, Harrod KS
Immunity & ageing : I & A 2014 Mar 19;11(1):4
Immunity & ageing : I & A 2014 Mar 19;11(1):4
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Both HLA-B*57 and plasma HIV RNA levels contribute to the HIV-specific CD8+ T cell response in HIV controllers.
Lécuroux C, Sáez-Cirión A, Girault I, Versmisse P, Boufassa F, Avettand-Fenoël V, Rouzioux C, Meyer L, Pancino G, Lambotte O, Sinet M, Venet A
Journal of virology 2014 Jan;88(1):176-87
Journal of virology 2014 Jan;88(1):176-87
Peripheral blood CD56(bright) NK cells respond to stem cell factor and adhere to its membrane-bound form after upregulation of c-kit.
Pradier A, Tabone-Eglinger S, Huber V, Bosshard C, Rigal E, Wehrle-Haller B, Roosnek E
European journal of immunology 2014 Feb;44(2):511-20
European journal of immunology 2014 Feb;44(2):511-20
Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango.
Hoyer S, Prommersberger S, Pfeiffer IA, Schuler-Thurner B, Schuler G, Dörrie J, Schaft N
European journal of immunology 2014 Dec;44(12):3543-59
European journal of immunology 2014 Dec;44(12):3543-59
TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys.
Osuna CE, Gonzalez AM, Chang HH, Hung AS, Ehlinger E, Anasti K, Alam SM, Letvin NL
PLoS pathogens 2014 Apr;10(4):e1004069
PLoS pathogens 2014 Apr;10(4):e1004069
MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial.
Romano E, Michielin O, Voelter V, Laurent J, Bichat H, Stravodimou A, Romero P, Speiser DE, Triebel F, Leyvraz S, Harari A
Journal of translational medicine 2014 Apr 12;12:97
Journal of translational medicine 2014 Apr 12;12:97
Bone marrow T cells from the femur are similar to iliac crest derived cells in old age and represent a useful tool for studying the aged immune system.
Pritz T, Landgraf-Rauf K, Herndler-Brandstetter D, Rauf R, Lair J, Gassner R, Weinberger B, Krismer M, Grubeck-Loebenstein B
Immunity & ageing : I & A 2013 May 4;10(1):17
Immunity & ageing : I & A 2013 May 4;10(1):17
CCR5 is a receptor for Staphylococcus aureus leukotoxin ED.
Alonzo F 3rd, Kozhaya L, Rawlings SA, Reyes-Robles T, DuMont AL, Myszka DG, Landau NR, Unutmaz D, Torres VJ
Nature 2013 Jan 3;493(7430):51-5
Nature 2013 Jan 3;493(7430):51-5
CCR2(+)CCR5(+) T cells produce matrix metalloproteinase-9 and osteopontin in the pathogenesis of multiple sclerosis.
Sato W, Tomita A, Ichikawa D, Lin Y, Kishida H, Miyake S, Ogawa M, Okamoto T, Murata M, Kuroiwa Y, Aranami T, Yamamura T
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov 15;189(10):5057-65
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov 15;189(10):5057-65
Biomarkers on melanoma patient T cells associated with ipilimumab treatment.
Wang W, Yu D, Sarnaik AA, Yu B, Hall M, Morelli D, Zhang Y, Zhao X, Weber JS
Journal of translational medicine 2012 Jul 12;10:146
Journal of translational medicine 2012 Jul 12;10:146
The CD46-Jagged1 interaction is critical for human TH1 immunity.
Le Friec G, Sheppard D, Whiteman P, Karsten CM, Shamoun SA, Laing A, Bugeon L, Dallman MJ, Melchionna T, Chillakuri C, Smith RA, Drouet C, Couzi L, Fremeaux-Bacchi V, Köhl J, Waddington SN, McDonnell JM, Baker A, Handford PA, Lea SM, Kemper C
Nature immunology 2012 Dec;13(12):1213-21
Nature immunology 2012 Dec;13(12):1213-21
Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M
European journal of immunology 2012 Apr;42(4):936-45
European journal of immunology 2012 Apr;42(4):936-45
Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation.
Barbosa RR, Silva SP, Silva SL, Melo AC, Pedro E, Barbosa MP, Pereira-Santos MC, Victorino RM, Sousa AE
PloS one 2011;6(8):e22848
PloS one 2011;6(8):e22848
Identification of human NK17/NK1 cells.
Pandya AD, Al-Jaderi Z, Høglund RA, Holmøy T, Harbo HF, Norgauer J, Maghazachi AA
PloS one 2011;6(10):e26780
PloS one 2011;6(10):e26780
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
Bosco MC, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, Eva A, Novelli F, Cappello P, Giovarelli M, Varesio L
Blood 2011 Mar 3;117(9):2625-39
Blood 2011 Mar 3;117(9):2625-39
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
Jones GW, McLoughlin RM, Hammond VJ, Parker CR, Williams JD, Malhotra R, Scheller J, Williams AS, Rose-John S, Topley N, Jones SA
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 15;184(4):2130-9
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 15;184(4):2130-9
CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response.
Zhang HH, Song K, Rabin RL, Hill BJ, Perfetto SP, Roederer M, Douek DC, Siegel RM, Farber JM
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):6646-63
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):6646-63
CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia.
Berrih-Aknin S, Ruhlmann N, Bismuth J, Cizeron-Clairac G, Zelman E, Shachar I, Dartevelle P, de Rosbo NK, Le Panse R
Annals of neurology 2009 Oct;66(4):521-31
Annals of neurology 2009 Oct;66(4):521-31
Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells.
Pedersen AW, Holmstrøm K, Jensen SS, Fuchs D, Rasmussen S, Kvistborg P, Claesson MH, Zocca MB
Clinical and experimental immunology 2009 Jul;157(1):48-59
Clinical and experimental immunology 2009 Jul;157(1):48-59
Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.
Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Makino H, Ranjan P, Minakuchi K, Sone S
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 15;183(12):8176-85
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 15;183(12):8176-85
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.
Dulphy N, Haas P, Busson M, Belhadj S, Peffault de Latour R, Robin M, Carmagnat M, Loiseau P, Tamouza R, Scieux C, Rabian C, Di Santo JP, Charron D, Janin A, Socié G, Toubert A
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):2227-37
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):2227-37
Intravenous immunoglobulins suppress T-cell priming by modulating the bidirectional interaction between dendritic cells and natural killer cells.
Tha-In T, Metselaar HJ, Tilanus HW, Groothuismink ZM, Kuipers EJ, de Man RA, Kwekkeboom J
Blood 2007 Nov 1;110(9):3253-62
Blood 2007 Nov 1;110(9):3253-62
Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.
Conrad C, Boyman O, Tonel G, Tun-Kyi A, Laggner U, de Fougerolles A, Kotelianski V, Gardner H, Nestle FO
Nature medicine 2007 Jul;13(7):836-42
Nature medicine 2007 Jul;13(7):836-42
Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection.
Fluur C, De Milito A, Fry TJ, Vivar N, Eidsmo L, Atlas A, Federici C, Matarrese P, Logozzi M, Rajnavölgyi E, Mackall CL, Fais S, Chiodi F, Rethi B
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 15;178(8):5340-50
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 15;178(8):5340-50
Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
Immunology 2004 Jun;112(2):274-89
Immunology 2004 Jun;112(2):274-89
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of CCR7 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A) and either (A) Mouse Anti-Human CCR7 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB197F) or (B) Mouse IgG2A Fluorescein Isotype Control (Catalog # IC003F). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR7 in HEK293 Human Cell Line Transfected with Human CCR7 and eGFP by Flow Cytometry. The specificity of Mouse Anti-Human CCR7 Clone 150503 was demonstrated by its ability to react with (A) HEK293 human embryonic kidney cell line transfected with human CCR7 and not react with (B) irrelevant HEK293 transfectants. Antibody binding was monitored using Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).
