ABIN361945

antibody from antibodies-online

Targeting: ELK1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN361945

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN361945, RRID:AB_10956440

Product name

anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer389) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer389 (P-R-S (p) -P-A) derived from Human Elk-1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer389

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Transcriptional regulation by extracellular signals: mechanisms and specificity.

Hill CS, Treisman R
Cell 1995 Jan 27;80(2):199-211

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Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

Cavigelli M, Dolfi F, Claret FX, Karin M
The EMBO journal 1995 Dec 1;14(23):5957-64

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Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2.

Kortenjann M, Thomae O, Shaw PE
Molecular and cellular biology 1994 Jul;14(7):4815-24

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Activation of ternary complex factor Elk-1 by MAP kinases.

Janknecht R, Ernst WH, Pingoud V, Nordheim A
The EMBO journal 1993 Dec 15;12(13):5097-104

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The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain.

Marais R, Wynne J, Treisman R
Cell 1993 Apr 23;73(2):381-93