Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN196875 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (pSer32), (pSer36) antibody
- Antibody type
- Polyclonal
- Description
- Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer32, pSer36
- Vial size
- 50 μL
- Storage
- Store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage.
A role for ATR in the DNA damage-induced phosphorylation of p53.
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization.
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53.
Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW
Science (New York, N.Y.) 2000 Mar 10;287(5459):1824-7
Science (New York, N.Y.) 2000 Mar 10;287(5459):1824-7
Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage.
Chehab NH, Malikzay A, Stavridi ES, Halazonetis TD
Proceedings of the National Academy of Sciences of the United States of America 1999 Nov 23;96(24):13777-82
Proceedings of the National Academy of Sciences of the United States of America 1999 Nov 23;96(24):13777-82
A role for ATR in the DNA damage-induced phosphorylation of p53.
Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, Shieh SY, Taya Y, Prives C, Abraham RT
Genes & development 1999 Jan 15;13(2):152-7
Genes & development 1999 Jan 15;13(2):152-7
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization.
Shieh SY, Taya Y, Prives C
The EMBO journal 1999 Apr 1;18(7):1815-23
The EMBO journal 1999 Apr 1;18(7):1815-23
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53.
Honda R, Tanaka H, Yasuda H
FEBS letters 1997 Dec 22;420(1):25-7
FEBS letters 1997 Dec 22;420(1):25-7
No comments: Submit comment
No validations: Submit validation data