ABIN966777

antibody from antibodies-online

Targeting: RPS6KB1 p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966777

Provider

antibodies-online

Product name

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human p70 S6 Kinase around the phosphorylation site of serine 424 (P-V-SP-P-V).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100 µg

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis.

Le XF, Hittelman WN, Liu J, McWatters A, Li C, Mills GB, Bast RC Jr
Oncogene 2003 Jan 30;22(4):484-97

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Persistant unconjugated hyperbilirubinemia in an infant with crigler-najjar syndrome type I.

Kulkarni ML, C NR
Indian pediatrics 2003 Dec;40(12):1209-10

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Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes.

Krause U, Bertrand L, Hue L
European journal of biochemistry / FEBS 2002 Aug;269(15):3751-9

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Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt.

Eguchi S, Iwasaki H, Ueno H, Frank GD, Motley ED, Eguchi K, Marumo F, Hirata Y, Inagami T
The Journal of biological chemistry 1999 Dec 24;274(52):36843-51

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Cdc2-cyclin B phosphorylates p70 S6 kinase on Ser411 at mitosis.

Papst PJ, Sugiyama H, Nagasawa M, Lucas JJ, Maller JL, Terada N
The Journal of biological chemistry 1998 Jun 12;273(24):15077-84