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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Immunohistochemistry [1]
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- Product number
- A01384 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-PKR(Ab-446) EIF2AK2 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for PKR/EIF2AK2 detection. Host: Rabbit.Size: 100μl. Tested applications: IF. Reactive species: Human. PKR/EIF2AK2 information: Molecular Weight: 62094 MW; Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Nuclear localization is elevated in acute leukemia, myelodysplastic syndrome (MDS), melanoma, breast, colon, prostate and lung cancer patient samples or cell lines as well as neurocytes from advanced Creutzfeldt-Jakob disease patients; Tissue Specificity: Highly expressed in thymus, spleen and bone marrow compared to non-hematopoietic tissues such as small intestine, liver, or kidney tissues. Colocalizes with GSK3B and TAU in the Alzheimer disease (AD) brain. Elevated levels seen in breast and colon carcinomas,and which correlates with tumor progression and invasiveness or risk of progression.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Vial size
- 100μl
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquoted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PKR(Ab-446) antibody A01384(left) or the same antibody preincubated with blocking peptide(right).
- Additional image
