ABIN965489

antibody from antibodies-online

Targeting: EIF4EBP1 4E-BP1, PHAS-I

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965489

Provider

antibodies-online

Product name

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized non-phosphopeptide derived from human 4E-BP1 around the phosphorylation site of threonine 45 (S-T-TP-P-G).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100 µg

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.

Moody CA, Scott RS, Amirghahari N, Nathan CO, Young LS, Dawson CW, Sixbey JW
Journal of virology 2005 May;79(9):5499-506

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex.

Brugarolas J, Lei K, Hurley RL, Manning BD, Reiling JH, Hafen E, Witters LA, Ellisen LW, Kaelin WG Jr
Genes & development 2004 Dec 1;18(23):2893-904

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Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.

Kumar V, Pandey P, Sabatini D, Kumar M, Majumder PK, Bharti A, Carmichael G, Kufe D, Kharbanda S
The EMBO journal 2000 Mar 1;19(5):1087-97

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1.

Burnett PE, Barrow RK, Cohen NA, Snyder SH, Sabatini DM
Proceedings of the National Academy of Sciences of the United States of America 1998 Feb 17;95(4):1432-7

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.

Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N
Genes & development 1998 Feb 15;12(4):502-13