Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN393552 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Histone Deacetylase 3 (HDAC3) (AA 319-429) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Epitope
- AA 319-429
- Isotype
- IgG
- Antibody clone number
- 2A3
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin.
Class I histone deacetylases 1, 2 and 3 are highly expressed in classical Hodgkin's lymphoma.
Association of histone deacetylase genes with schizophrenia in Korean population.
Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy.
Down-regulation of PROS1 gene expression by 17beta-estradiol via estrogen receptor alpha (ERalpha)-Sp1 interaction recruiting receptor-interacting protein 140 and the corepressor-HDAC3 complex.
Hayashi A, Horiuchi A, Kikuchi N, Hayashi T, Fuseya C, Suzuki A, Konishi I, Shiozawa T
International journal of cancer 2010 Sep 1;127(6):1332-46
International journal of cancer 2010 Sep 1;127(6):1332-46
Class I histone deacetylases 1, 2 and 3 are highly expressed in classical Hodgkin's lymphoma.
Adams H, Fritzsche FR, Dirnhofer S, Kristiansen G, Tzankov A
Expert opinion on therapeutic targets 2010 Jun;14(6):577-84
Expert opinion on therapeutic targets 2010 Jun;14(6):577-84
Association of histone deacetylase genes with schizophrenia in Korean population.
Kim T, Park JK, Kim HJ, Chung JH, Kim JW
Psychiatry research 2010 Jul 30;178(2):266-9
Psychiatry research 2010 Jul 30;178(2):266-9
Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy.
Yang Z, Zhou L, Wu LM, Xie HY, Zhang F, Zheng SS
Clinical chemistry and laboratory medicine 2010 Dec;48(12):1785-91
Clinical chemistry and laboratory medicine 2010 Dec;48(12):1785-91
Down-regulation of PROS1 gene expression by 17beta-estradiol via estrogen receptor alpha (ERalpha)-Sp1 interaction recruiting receptor-interacting protein 140 and the corepressor-HDAC3 complex.
Suzuki A, Sanda N, Miyawaki Y, Fujimori Y, Yamada T, Takagi A, Murate T, Saito H, Kojima T
The Journal of biological chemistry 2010 Apr 30;285(18):13444-53
The Journal of biological chemistry 2010 Apr 30;285(18):13444-53
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC