MAB269-100

antibody from R&D Systems

Targeting: IL1R1 CD121A, D2S1473, IL1R, IL1RA

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

MAB269-100

Provider

R&D Systems

Product name

Human IL-1 RI Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from ascites. Detects recombinant human (rh)IL-1 RI in direct ELISAs and Western blots. In Western blots, no cross-reactivity was observed with rhIL-1 RII, rhIL-1 R5, or rmIL-1 RI.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

35730

Vial size

100 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition.

Siddiqui I, Erreni M, Kamal MA, Porta C, Marchesi F, Pesce S, Pasqualini F, Schiarea S, Chiabrando C, Mantovani A, Allavena P
Oncoimmunology 2018;7(2):e1388485

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Chorionic gonadotropin down-regulates the expression of the decoy inhibitory interleukin 1 receptor type II in human endometrial epithelial cells.

Herrmann-Lavoie C, Rao CV, Akoum A
Endocrinology 2007 Nov;148(11):5377-84

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Immunolocalization of interleukin-1 receptors in the sarcolemma and nuclei of skeletal muscle in patients with idiopathic inflammatory myopathies.

Grundtman C, Salomonsson S, Dorph C, Bruton J, Andersson U, Lundberg IE
Arthritis and rheumatism 2007 Feb;56(2):674-87