Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [4]
- Flow cytometry [1]
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- Product number
- NBP2-33102 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal NF-H Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. This MAb reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Porcine
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: NF-H Antibody (NF421) - Azide and BSA Free [NBP2-33102] - Formalin-fixed, paraffin-embedded human cerebellum stained with Neurofilament NF421 antibody (1:200), peroxidase-conjugate and DAB chromogen.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: NF-H Antibody (NF421) - Azide and BSA Free [NBP2-33102] - Formalin-fixed, paraffin-embedded Rat Cerebellum stained with Neurofilament Monoclonal Antibody (RT-91).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: NF-H Antibody (NF421) - Azide and BSA Free [NBP2-33102] - Formalin-fixed, paraffin-embedded Rat Cerebellum stained with NF-H Antibody (NF421).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: NF-H Antibody (NF421) - Azide and BSA Free [NBP2-33102] - Formalin-fixed, paraffin-embedded human cerebellum stained with neurofilament monoclonal Antibody (RT-97)
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: NF-H Antibody (NF421) - Azide and BSA Free [NBP2-33102] - Flow Cytometric Analysis of HEK293 cells using NF-H Antibody (NF421) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype control (Red).