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LearnPAB12462
antibody from Abnova Corporation
Targeting: CDKN2A
ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- PAB12462 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12462, RRID:AB_10549805
- Product name
- CDKN2A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CDKN2A.
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis.
Frequent p16-independent inactivation of p14ARF in human melanoma.
Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues.
N-terminal polyubiquitination and degradation of the Arf tumor suppressor.
The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription.
Wang WH, Hullinger RL, Andrisani OM
The Journal of biological chemistry 2008 Sep 12;283(37):25455-67
The Journal of biological chemistry 2008 Sep 12;283(37):25455-67
Frequent p16-independent inactivation of p14ARF in human melanoma.
Freedberg DE, Rigas SH, Russak J, Gai W, Kaplow M, Osman I, Turner F, Randerson-Moor JA, Houghton A, Busam K, Timothy Bishop D, Bastian BC, Newton-Bishop JA, Polsky D
Journal of the National Cancer Institute 2008 Jun 4;100(11):784-95
Journal of the National Cancer Institute 2008 Jun 4;100(11):784-95
Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues.
Miller SJ, Rangwala F, Williams J, Ackerman P, Kong S, Jegga AG, Kaiser S, Aronow BJ, Frahm S, Kluwe L, Mautner V, Upadhyaya M, Muir D, Wallace M, Hagen J, Quelle DE, Watson MA, Perry A, Gutmann DH, Ratner N
Cancer research 2006 Mar 1;66(5):2584-91
Cancer research 2006 Mar 1;66(5):2584-91
N-terminal polyubiquitination and degradation of the Arf tumor suppressor.
Kuo ML, den Besten W, Bertwistle D, Roussel MF, Sherr CJ
Genes & development 2004 Aug 1;18(15):1862-74
Genes & development 2004 Aug 1;18(15):1862-74
The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription.
Fatyol K, Szalay AA
The Journal of biological chemistry 2001 Jul 27;276(30):28421-9
The Journal of biological chemistry 2001 Jul 27;276(30):28421-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CDKN2A in HeLa whole cell lysate CDKN2A polyclonal antibody (Cat # PAB12462).
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CDKN2A in lysates of cells that were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY CDKN2A cDNA using CDKN2A polyclonal antibody (Cat # PAB12462).
