Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
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- Product number
- PA5-16272 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-TGM2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- PA5-16272 targets Transglutaminase II in IHC (P), IP, and WB applications and shows reactivity with Human, mouse, and Rat samples. The PA5-16272 immunogen is recombinant full length human TGase II.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 500 µL
- Concentration
- 1 mg/mL
- Storage
- 4° C
Submitted references Dermatan sulfate is a player in the transglutaminase 2 interaction network.
Exercise, vascular stiffness, and tissue transglutaminase.
A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis.
Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.
Transglutaminase 2 interaction with small heat shock proteins mediate cell survival upon excitotoxic stress.
Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formation.
The redox state of transglutaminase 2 controls arterial remodeling.
Wisowski G, Koźma EM, Bielecki T, Pudełko A, Olczyk K
PloS one 2017;12(2):e0172263
PloS one 2017;12(2):e0172263
Exercise, vascular stiffness, and tissue transglutaminase.
Steppan J, Sikka G, Jandu S, Barodka V, Halushka MK, Flavahan NA, Belkin AM, Nyhan D, Butlin M, Avolio A, Berkowitz DE, Santhanam L
Journal of the American Heart Association 2014 Apr 10;3(2):e000599
Journal of the American Heart Association 2014 Apr 10;3(2):e000599
A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis.
Wang Z, Perez M, Caja S, Melino G, Johnson TS, Lindfors K, Griffin M
Cell death & disease 2013 Sep 19;4:e808
Cell death & disease 2013 Sep 19;4:e808
Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.
Jung SM, Jandu S, Steppan J, Belkin A, An SS, Pak A, Choi EY, Nyhan D, Butlin M, Viegas K, Avolio A, Berkowitz DE, Santhanam L
American journal of physiology. Heart and circulatory physiology 2013 Sep 15;305(6):H803-10
American journal of physiology. Heart and circulatory physiology 2013 Sep 15;305(6):H803-10
Transglutaminase 2 interaction with small heat shock proteins mediate cell survival upon excitotoxic stress.
Caccamo D, Condello S, Ferlazzo N, Currò M, Griffin M, Ientile R
Amino acids 2013 Jan;44(1):151-9
Amino acids 2013 Jan;44(1):151-9
Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formation.
van den Akker J, van Weert A, Afink G, Bakker EN, van der Pol E, Böing AN, Nieuwland R, VanBavel E
Amino acids 2012 Feb;42(2-3):961-73
Amino acids 2012 Feb;42(2-3):961-73
The redox state of transglutaminase 2 controls arterial remodeling.
van den Akker J, VanBavel E, van Geel R, Matlung HL, Guvenc Tuna B, Janssen GM, van Veelen PA, Boelens WC, De Mey JG, Bakker EN
PloS one 2011;6(8):e23067
PloS one 2011;6(8):e23067
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot of Transglutaminase II using Transglutaminase II Polyclonal Antibody (Product # PA5-16272) on HUVEC Cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of Transglutaminase II using Transglutaminase II Polyclonal Antibody (Product # PA5-16272) on Native Human MCF-7 Cells.