NBP2-33094IR

antibody from Novus Biologicals

Targeting: MAGEA1 CT1.1, MAGE1, MGC9326

ELISA (Data presented on provider website)

Antibody Data

Product number

NBP2-33094IR

Provider

Novus Biologicals

Product name

Mouse Monoclonal MAGE 1 Antibody

Antibody type

Monoclonal

Description

Protein G purified. Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Reactivity

Human, Rat, Canine

Host

Mouse

Conjugate

Near infrared dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.