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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Immunohistochemistry [1]
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- Product number
- NBP2-44646 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal CD43/Sialophorin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 7 ml
- Storage
- Store at 4C.
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- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody (DF-T1) - IHC-Prediluted [NBP2-44646] - Formalin-paraffin human spleen stained with CD43 Ab (DF-T1).
