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antibody from Invitrogen Antibodies
Targeting: RUNX2
AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [2]
- Other assay [1]
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- Product number
- 41-1400 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- RUNX2 Monoclonal Antibody (ZR002)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- ZR002
- Vial size
- 100 µg
- Concentration
- 0.5 mg/mL
- Storage
- -20°C
Submitted references Gel based in vitro 3D model exploring the osteocytic potentiality of human CD34(+) stem cells.
Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition.
Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation.
Srikanth L, Sunitha MM, Kumar PS, Chandrasekhar C, Vengamma B, Sarma PV
Molecular biology reports 2016 Nov;43(11):1233-1242
Molecular biology reports 2016 Nov;43(11):1233-1242
Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition.
Pilia M, Guda T, Shiels SM, Appleford MR
Journal of biological engineering 2013 Oct 3;7(1):23
Journal of biological engineering 2013 Oct 3;7(1):23
Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation.
Baniwal SK, Little GH, Chimge NO, Frenkel B
Journal of cellular physiology 2012 May;227(5):2276-82
Journal of cellular physiology 2012 May;227(5):2276-82
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of Saos-2 cell lysates using Zymed Ms anti-Runx2 (Product # 41-1400).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of Saos-2 cell lysates using Zymed Ms anti-Runx2 (Product # 41-1400).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 6 HFOb cell count and differentiation assay for the four groups tested. (A) cell count for the Flat, 500, 250 and 100 mc throughout four time points: 6, 12, 18, and 24 days. No proliferation is seen throughout the four weeks. There is a significant decrease in cells found on the 100 group at the last time point. Also seen are the differentiation markers RUNX2 (B) , ALP (C) , OPN (D) . The RUNX2 groups do not show any significant difference between the groups although we can see a trend in which the 250 mum diameter microchannels have lower levels than the rest of the groups. The ALP activity shows two different peaks at day 12 and at day 24. At the last time point the 500 and 250 mum diameter microchannels showed a significant higher ALP activity than the Flat control group. The OPN levels do show significant difference on day 18 between the 100 mum diameter microchannels and the control group. At day 24 the significant difference was seen between the 500 mum and the Flat. All data shown as mean +- standard error. * P < 0.05; ^ P < 0.01; # P < 0.001.
