NBP2-47921JF549

antibody from Novus Biologicals
Targeting: CCND1 BCL1, D11S287E, PRAD1, U21B31
Provider product page for NBP2-47921JF549
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-47921JF549 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Cyclin D1 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C in the dark.
CCND1 protein structure - NBP2-47921JF549 shown in red.