NBP2-33150JF549

antibody from Novus Biologicals

Targeting: MLANA MART1

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

NBP2-33150JF549

Provider

Novus Biologicals

Product name

Mouse Monoclonal Melan-A/MART-1 Antibody

Antibody type

Monoclonal

Description

Protein G purified. This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.