ADI-SPA-816-J

antibody from Enzo Life Sciences

Targeting: HSPA8 HSC70, HSC71, HSP73, HSPA10

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ADI-SPA-816-J

Provider

Enzo Life Sciences

Proper citation

Enzo Life Sciences Cat#ADI-SPA-816-J, RRID:AB_11178696

Product name

HSC70/HSP73 polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Protein A affinity purified.

Reactivity

Human, Mouse, Rat, Bovine, Canine, Guinea Pig, Hamster, Porcine, Rabbit, Sheep, Simian

Host

Rabbit

Vial size

1 mg

Storage

-20°C

Handling

Avoid freeze/thaw cycles.

References

Submitted references

HSPB8 and the Cochaperone BAG3 Are Highly Expressed During the Synthetic Phase of Rat Myometrium Programming During Pregnancy.

Marsh NM, Wareham A, White BG, Miskiewicz EI, Landry J, MacPhee DJ
Biology of reproduction 2015 May;92(5):131

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Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.

Kocalis HE, Hagan SL, George L, Turney MK, Siuta MA, Laryea GN, Morris LC, Muglia LJ, Printz RL, Stanwood GD, Niswender KD
Molecular metabolism 2014 Jul;3(4):394-407

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AICAR-induced activation of AMPK negatively regulates myotube hypertrophy through the HSP72-mediated pathway in C2C12 skeletal muscle cells.

Egawa T, Ohno Y, Goto A, Ikuta A, Suzuki M, Ohira T, Yokoyama S, Sugiura T, Ohira Y, Yoshioka T, Goto K
American journal of physiology. Endocrinology and metabolism 2014 Feb;306(3):E344-54

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Rescue of atypical protein kinase C in epithelia by the cytoskeleton and Hsp70 family chaperones.

Mashukova A, Oriolo AS, Wald FA, Casanova ML, Kröger C, Magin TM, Omary MB, Salas PJ
Journal of cell science 2009 Jul 15;122(Pt 14):2491-503

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Downregulation of renal TonEBP in hypokalemic rats.

Jeon US, Han KH, Park SH, Lee SD, Sheen MR, Jung JY, Kim WY, Sands JM, Kim J, Kwon HM
American journal of physiology. Renal physiology 2007 Jul;293(1):F408-15

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Tid1 isoforms are mitochondrial DnaJ-like chaperones with unique carboxyl termini that determine cytosolic fate.

Lu B, Garrido N, Spelbrink JN, Suzuki CK
The Journal of biological chemistry 2006 May 12;281(19):13150-8

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Priming biologically active antibody responses against an isolated, conformational viral epitope by DNA vaccination.

Riedl P, El-Kholy S, Reimann J, Schirmbeck R
Journal of immunology (Baltimore, Md. : 1950) 2002 Aug 1;169(3):1251-60

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Cancer-associated retinopathy induced by both anti-recoverin and anti-hsc70 antibodies in vivo.

Ohguro H, Ogawa K, Maeda T, Maeda A, Maruyama I
Investigative ophthalmology & visual science 1999 Dec;40(13):3160-7

Immunocytochemistry

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Western Blot Analysis of Hsc70 (Hsp73): Lane 1: MWM, Lane 2: HSC70/HSP70 (bovine), (recombinant) (Cat #: ADI-SPP-751) Lane 3: HSP70/HSP72 (human), (recombinant) (Cat #: ADI-NSP-555), Lane 4: HeLa Cell Lysate, Lane 5: L929 Cell Lysate, Lane 6: PC-12 Cell Lysate, Lane 7: CHO-K1 Cell Lysate, Lane 8: RK-13 Cell Lysate

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunohistochemistry analysis of human spleen tissue stained with HSC70/HSP73, pAb at 10µg/ml.