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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP2-54365C - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Filaggrin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 ul
- Storage
- Store at 4C in the dark.
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