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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN358411 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tuberous Sclerosis 2 (TSC2) (pSer1420) antibody
- Antibody type
- Polyclonal
- Description
- Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer1420
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Genotype and psychological phenotype in tuberous sclerosis.
Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways.
Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
Li Y, Inoki K, Guan KL
Molecular and cellular biology 2004 Sep;24(18):7965-75
Molecular and cellular biology 2004 Sep;24(18):7965-75
Genotype and psychological phenotype in tuberous sclerosis.
Lewis JC, Thomas HV, Murphy KC, Sampson JR
Journal of medical genetics 2004 Mar;41(3):203-7
Journal of medical genetics 2004 Mar;41(3):203-7
Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways.
Birchenall-Roberts MC, Fu T, Bang OS, Dambach M, Resau JH, Sadowski CL, Bertolette DC, Lee HJ, Kim SJ, Ruscetti FW
The Journal of biological chemistry 2004 Jun 11;279(24):25605-13
The Journal of biological chemistry 2004 Jun 11;279(24):25605-13
Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M, Cash T, Cheung M, Robertson GP, Astrinidis A, Henske EP
The Journal of biological chemistry 2004 Jul 16;279(29):29930-7
The Journal of biological chemistry 2004 Jul 16;279(29):29930-7
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
Corradetti MN, Inoki K, Bardeesy N, DePinho RA, Guan KL
Genes & development 2004 Jul 1;18(13):1533-8
Genes & development 2004 Jul 1;18(13):1533-8
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