NBP2-34264-0.1mg

antibody from Novus Biologicals
Targeting: IVL
Provider product page for NBP2-34264-0.1mg
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-34264-0.1mg - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Involucrin Antibody
Antibody type
Monoclonal
Description
Protein A purified. It recognizes a protein of 66kDa-170kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this MAb reacts with a 120kDa protein. It stains the involucrin in a variety of sizes: 170kDa in MCF-7 cells, a doublet of ~115kDa and 150kDa in gorilla and owl monkey, 66kDa in dog, and a doublet of 105kDa in pig. Its epitope maps between codon 421-568 of human involucrin. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal
Reactivity
Human, Mouse, Canine, Porcine, Simian
Host
Mouse
Isotype
IgG
Vial size
0.1 mg
Concentration
0.2 mg/ml
Storage
Store at 4C.
IVL protein structure - NBP2-34264-0.1mg shown in red.