NBP2-47725G

antibody from Novus Biologicals

Targeting: IL2RA CD25, IDDM10, IL2R

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NBP2-47725G

Provider

Novus Biologicals

Product name

Mouse Monoclonal CD25/IL-2R alpha Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Reactivity

Human

Host

Mouse

Conjugate

Green dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.