NBP2-52661AF488

antibody from Novus Biologicals

Targeting: IL2RA CD25, IDDM10, IL2R

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NBP2-52661AF488

Provider

Novus Biologicals

Product name

Rabbit Monoclonal CD25/IL-2R alpha Antibody

Antibody type

Monoclonal

Description

Protein A purified. Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.

Reactivity

Human

Host

Rabbit

Conjugate

Green dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.