Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP2-75902-0.2mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Human Monoclonal CD25/IL-2R alpha Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
- Reactivity
- Human
- Host
- Human
- Isotype
- IgG
- Vial size
- 0.2 mg
- Storage
- Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry: CD25/IL-2 R alpha Antibody (Basiliximab) [NBP2-75902] - Formalin fixed rat spleen slices were were stained with a NBP2-75902 at 5 ug/ml. The anti-human CD25 antibody NBP2-75902 also shows some cross-reactivity with rat in IHC.