ABIN1106134

antibody from antibodies-online

Targeting: IL2RA CD25, IDDM10, IL2R

Flow cytometry (Supportive data in Antibodypedia)

Functional assay (Recommended by provider)

Antibody Data

Product number

ABIN1106134

Provider

antibodies-online

Product name

anti-Interleukin 2 Receptor, alpha (IL2RA) antibody

Antibody type

Monoclonal

Description

Ion Exchange Chromatography.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

B-B10

Vial size

0.2 mg

Storage

Store the antibody undiluted at 2-8°C.

References

Submitted references

A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines.

Regeer RR, Markovich D
American journal of physiology. Cell physiology 2004 Aug;287(2):C365-72

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA
Immunity 2000 Nov;13(5):715-25

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Cytogenetic abnormalities in primary myelodysplastic syndrome are highly predictive of outcome after allogeneic bone marrow transplantation.

Nevill TJ, Fung HC, Shepherd JD, Horsman DE, Nantel SH, Klingemann HG, Forrest DL, Toze CL, Sutherland HJ, Hogge DE, Naiman SC, Le A, Brockington DA, Barnett MJ
Blood 1998 Sep 15;92(6):1910-7

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Successful treatment of invasive aspergillosis in chronic granulomatous disease by bone marrow transplantation, granulocyte colony-stimulating factor-mobilized granulocytes, and liposomal amphotericin-B.

Ozsahin H, von Planta M, Müller I, Steinert HC, Nadal D, Lauener R, Tuchschmid P, Willi UV, Ozsahin M, Crompton NE, Seger RA
Blood 1998 Oct 15;92(8):2719-24

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Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells.

Groux H, Bigler M, de Vries JE, Roncarolo MG
Journal of immunology (Baltimore, Md. : 1950) 1998 Apr 1;160(7):3188-93

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Interleukin-15 triggers the proliferation and cytotoxicity of granular lymphocytes in patients with lymphoproliferative disease of granular lymphocytes.

Zambello R, Facco M, Trentin L, Sancetta R, Tassinari C, Perin A, Milani A, Pizzolo G, Rodeghiero F, Agostini C, Meazza R, Ferrini S, Semenzato G
Blood 1997 Jan 1;89(1):201-11

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Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients.

Racadot E, Milpied N, Bordigoni P, Cahn JY, Plouvier E, Lioure B, Lutz P, Wijdenes J, Herve P
Bone marrow transplantation 1995 May;15(5):669-77

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CD4 and CD25 monoclonal antibody cocktail in kidney transplant rejection prophylaxis: clinical results of a pilot study.

Mousson C, Tanter Y, Racadot E, Wijdenes J, Chalopin JM, Chevet D, Hervé P, Rifle G
Transplantation proceedings 1995 Apr;27(2):1727-8

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Outcome of lymphocyte subsets and cytokines during combined CD4/anti-IL-2R monoclonal antibody therapy in kidney transplantation.

Racadot E, Mousson C, Tanter Y, Wijdenes J, Rifle G, Herve P
Transplantation proceedings 1995 Apr;27(2):1672-3

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Treatment of steroid-resistant acute graft-versus-host disease with an anti-IL-2-receptor monoclonal antibody (BT 563) in children who received T cell-depleted, partially matched, related bone marrow transplants.

Herbelin C, Stephan JL, Donadieu J, Le Deist F, Racadot E, Wijdenes J, Fischer A
Bone marrow transplantation 1994 May;13(5):563-9

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Humanization of mouse anti-human IL-2 receptor antibody B-B10.

Nakatani T, Lone YC, Yamakawa J, Kanaoka M, Gomi H, Wijdenes J, Noguchi H
Protein engineering 1994 Mar;7(3):435-43

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B-B10 (anti-CD25)-saporin immunotoxin--a possible tool in graft-versus-host disease treatment.

Tazzari PL, Bolognesi A, De Totero D, Pileri S, Conte R, Wijdenes J, Hervé P, Soria M, Stirpe F, Gobbi M
Transplantation 1992 Aug;54(2):351-6

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Soluble CD8, IL-2 receptor, and tumor necrosis factor-alpha levels in steroid-resistant acute graft-versus-host disease. Relation with subsequent response to anti-IL-2 receptor monoclonal antibody treatment.

Tiberghien P, Racadot E, Lioure B, Delain M, Girard A, Wijdenes J, Plouvier E, Flesch M, Cahn JY, Herve P
Transplantation 1991 Sep;52(3):475-80

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Immunotoxins constructed with anti-CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent anti-tumour effects against human Hodgkin cells in vitro and solid Hodgkin tumours in mice.

Engert A, Martin G, Amlot P, Wijdenes J, Diehl V, Thorpe P
International journal of cancer 1991 Sep 30;49(3):450-6

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[Therapy of multiple myeloma by allogeneic bone marrow transplantation].

Heyll A, Aul C, Söhngen D, Meckenstock G, Arning M, Wurm R, Schmitt G, Schneider W
Deutsche medizinische Wochenschrift (1946) 1991 May 31;116(22):852-6

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A semi-pharmaceutical approach for the preparation of an anti-IL2 receptor monoclonal antibody in the treatment of acute GvHD in a multicentric study.

Wijdenes J, Beliard R, Muot S, Herve P, Peters A
Developments in biological standardization 1990;71:103-11

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Treatment of corticosteroid resistant acute graft-versus-host disease by in vivo administration of anti-interleukin-2 receptor monoclonal antibody (B-B10)

Hervé P, Wijdenes J, Bergerat JP, Bordigoni P, Milpied N, Cahn JY, Clément C, Béliard R, Morel-Fourrier B, Racadot E
Blood 1990 Feb 15;75(4):1017-23

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Treatment of acute graft-versus-host disease with monoclonal antibody to IL-2 receptor.

Hervé P, Wijdenes J, Bergerat JP, Milpied N, Gaud C, Bordigoni P
Lancet (London, England) 1988 Nov 5;2(8619):1072-3

Flow cytometry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

FACS