ALX-805-046PF-C100

antibody from Enzo Life Sciences

Targeting: CD40 Bp50, p50, TNFRSF5

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ALX-805-046PF-C100

Provider

Enzo Life Sciences

Product name

CD40 (mouse) monoclonal antibody (FGK45) (preservative free)

Antibody type

Monoclonal

Antigen

Recombinant full length protein

Description

Protein G-affinity purified.

Reactivity

Mouse

Host

Rat

Isotype

IgG

Antibody clone number

FGK45

Vial size

100 μg

Storage

-20°C

Handling

Avoid freeze/thaw cycles.

References

Submitted references

ATAD5 deficiency decreases B cell division and Igh recombination.

Zanotti KJ, Maul RW, Castiblanco DP, Yang W, Choi YJ, Fox JT, Myung K, Saribasak H, Gearhart PJ
Journal of immunology (Baltimore, Md. : 1950) 2015 Jan 1;194(1):35-42

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CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema.

Shigeta A, Tada Y, Wang JY, Ishizaki S, Tsuyusaki J, Yamauchi K, Kasahara Y, Iesato K, Tanabe N, Takiguchi Y, Sakamoto A, Tokuhisa T, Shibuya K, Hiroshima K, West J, Tatsumi K
American journal of physiology. Lung cellular and molecular physiology 2012 Jul;303(2):L141-51

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Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific CD4+ T cell proliferation during the induction of inhalation tolerance.

Fear VS, Burchell JT, Lai SP, Wikstrom ME, Blank F, von Garnier C, Turner DJ, Sly PD, Holt PG, Strickland DS, Stumbles PA
Journal of immunology (Baltimore, Md. : 1950) 2011 Nov 1;187(9):4561-70

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Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs).

Yanai H, Chiba S, Ban T, Nakaima Y, Onoe T, Honda K, Ohdan H, Taniguchi T
Proceedings of the National Academy of Sciences of the United States of America 2011 Jul 12;108(28):11542-7

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Expression of cellular FLIP by B cells is required for their participation in an immune response.

Coffey F, Manser T
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):4871-9

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A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity.

Schroder WA, Le TT, Major L, Street S, Gardner J, Lambley E, Markey K, MacDonald KP, Fish RJ, Thomas R, Suhrbier A
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2663-70

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Identification and characterization of a lupus suppressor 129 locus on chromosome 3.

Carlucci F, Fossati-Jimack L, Dumitriu IE, Heidari Y, Walport MJ, Szajna M, Baruah P, Garden OA, Cook HT, Botto M
Journal of immunology (Baltimore, Md. : 1950) 2010 Jun 1;184(11):6256-65

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The pleckstrin homology domain adaptor protein Bam32/DAPP1 is required for germinal center progression.

Zhang TT, Al-Alwan M, Marshall AJ
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 1;184(1):164-72

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A role for cFLIP in B cell proliferation and stress MAPK regulation.

Zhang H, Rosenberg S, Coffey FJ, He YW, Manser T, Hardy RR, Zhang J
Journal of immunology (Baltimore, Md. : 1950) 2009 Jan 1;182(1):207-15

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Agonistic anti-CD40 antibody profoundly suppresses the immune response to infection with lymphocytic choriomeningitis virus.

Bartholdy C, Kauffmann SØ, Christensen JP, Thomsen AR
Journal of immunology (Baltimore, Md. : 1950) 2007 Feb 1;178(3):1662-70

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IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling.

Hellings PW, Kasran A, Bullens D, Overbergh L, Mathieu C, Heremans H, Matthys P, Boon L, Jorissen M, Ceuppens JL
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 15;177(8):5138-44

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In vivo and in vitro regulation of type I IFN synthesis by synergistic effects of CD40 and type II IFN.

Greene JA, DeVecchio JL, Gould MP, Auletta JJ, Heinzel FP
Journal of immunology (Baltimore, Md. : 1950) 2006 May 15;176(10):5995-6003

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Regulatory and effector T cell activation levels are prime determinants of in vivo immune regulation.

Billiard F, Litvinova E, Saadoun D, Djelti F, Klatzmann D, Cohen JL, Marodon G, Salomon BL
Journal of immunology (Baltimore, Md. : 1950) 2006 Aug 15;177(4):2167-74

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IRF-7 is the master regulator of type-I interferon-dependent immune responses.

Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T
Nature 2005 Apr 7;434(7034):772-7

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CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes.

McGregor CM, Schoenberger SP, Green EA
Proceedings of the National Academy of Sciences of the United States of America 2004 Jun 22;101(25):9345-50

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The antigen-presenting activity of fresh, adult parenchymal microglia and perivascular cells from retina.

Gregerson DS, Sam TN, McPherson SW
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 1;172(11):6587-97

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Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system.

Erlebacher A, Zhang D, Parlow AF, Glimcher LH
The Journal of clinical investigation 2004 Jul;114(1):39-48

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Anti-CD40 antibody induces antitumor and antimetastatic effects: the role of NK cells.

Turner JG, Rakhmilevich AL, Burdelya L, Neal Z, Imboden M, Sondel PM, Yu H
Journal of immunology (Baltimore, Md. : 1950) 2001 Jan 1;166(1):89-94

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Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process.

Mauri C, Mars LT, Londei M
Nature medicine 2000 Jun;6(6):673-9

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Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.

Rolink AG, Andersson J, Melchers F
European journal of immunology 1998 Nov;28(11):3738-48

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The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

Rolink A, Melchers F, Andersson J
Immunity 1996 Oct;5(4):319-30