ABIN968494

antibody from antibodies-online

Targeting: CD40 Bp50, p50, TNFRSF5

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN968494

Provider

antibodies-online

Product name

anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (AA 71-187) antibody

Antibody type

Monoclonal

Antigen

Human CD40

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

AA 71-187

Isotype

IgG

Antibody clone number

BC17

Vial size

50 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses.

Nguyen LT, Duncan GS, Mirtsos C, Ng M, Speiser DE, Shahinian A, Marino MW, Mak TW, Ohashi PS, Yeh WC
Immunity 1999 Sep;11(3):379-89

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Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb.

Morio T, Hanissian SH, Bacharier LB, Teraoka H, Nonoyama S, Seki M, Kondo J, Nakano H, Lee SK, Geha RS, Yata J
Immunity 1999 Sep;11(3):339-48

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Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.

Randall TD, Heath AW, Santos-Argumedo L, Howard MC, Weissman IL, Lund FE
Immunity 1998 Jun;8(6):733-42

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A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

Stamenkovic I, Clark EA, Seed B
The EMBO journal 1989 May;8(5):1403-10