ABIN5080375

Kang H, Jo A, Kim H, Khang R, Lee JY, Kim H, Park CH, Choi JY, Lee Y, Shin JH
Biochemical and biophysical research communications 2018 Jan 22;495(4):2498-2504

Dual mTORC1/mTORC2 blocker as a possible therapy for tauopathy in cellular model.

Salama M, Elhussiny M, Magdy A, Omran AG, Alsayed A, Ashry R, Mohamed W
Metabolic brain disease 2018 Apr;33(2):583-587

Whole genome expression profiling associates activation of unfolded protein response with impaired production and release of epinephrine after recurrent hypoglycemia.

Kim JL, La Gamma EF, Estabrook T, Kudrick N, Nankova BB
PloS one 2017;12(2):e0172789

Gene expression analyses reveal metabolic specifications in acute O₂ -sensing chemoreceptor cells.

Gao L, Bonilla-Henao V, García-Flores P, Arias-Mayenco I, Ortega-Sáenz P, López-Barneo J
The Journal of physiology 2017 Sep 15;595(18):6091-6120

Cardiovascular adaptation to hypoxia and the role of peripheral resistance.

Cowburn AS, Macias D, Summers C, Chilvers ER, Johnson RS
eLife 2017 Oct 19;6

Overexpression of Parkinson's Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology.

Xiong Y, Neifert S, Karuppagounder SS, Stankowski JN, Lee BD, Grima JC, Chen G, Ko HS, Lee Y, Swing D, Tessarollo L, Dawson TM, Dawson VL
eNeuro 2017 Mar-Apr;4(2)

Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.

Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A, Claret M
Cell metabolism 2017 Jun 6;25(6):1390-1399.e6

Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.

Shimohata A, Ishihara K, Hattori S, Miyamoto H, Morishita H, Ornthanalai G, Raveau M, Ebrahim AS, Amano K, Yamada K, Sago H, Akiba S, Mataga N, Murphy NP, Miyakawa T, Yamakawa K
Experimental neurology 2017 Jul;293:1-12

Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection.

Kang H, Khang R, Ham S, Jeong GR, Kim H, Jo M, Lee BD, Lee YI, Jo A, Park C, Kim H, Seo J, Paek SH, Lee YS, Choi JY, Lee Y, Shin JH
Oncotarget 2017 Jul 25;8(30):48603-48618

Assessment of the acquisition of executive function during the transition from adolescence to adulthood in male and female mice.

Shepard R, Beckett E, Coutellier L
Developmental cognitive neuroscience 2017 Dec;28:29-40

Altered Differentiation Potential of Gaucher's Disease iPSC Neuronal Progenitors due to Wnt/β-Catenin Downregulation.

Awad O, Panicker LM, Deranieh RM, Srikanth MP, Brown RA, Voit A, Peesay T, Park TS, Zambidis ET, Feldman RA
Stem cell reports 2017 Dec 12;9(6):1853-1867

Nociceptive DRG neurons express muscle lim protein upon axonal injury.

Levin E, Andreadaki A, Gobrecht P, Bosse F, Fischer D
Scientific reports 2017 Apr 4;7(1):643

Dopamine- and Tyrosine Hydroxylase-Immunoreactive Neurons in the Brain of the American Cockroach, Periplaneta americana.

Hamanaka Y, Minoura R, Nishino H, Miura T, Mizunami M
PloS one 2016;11(8):e0160531

Olfactory Sensory Activity Modulates Microglial-Neuronal Interactions during Dopaminergic Cell Loss in the Olfactory Bulb.

Grier BD, Belluscio L, Cheetham CE
Frontiers in cellular neuroscience 2016;10:178

Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines.

Januchowski R, Wojtowicz K, Sterzyſska K, Sosiſska P, Andrzejewska M, Zawierucha P, Nowicki M, Zabel M
The international journal of biochemistry & cell biology 2016 Sep;78:248-259

LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity.

Karuppagounder SS, Xiong Y, Lee Y, Lawless MC, Kim D, Nordquist E, Martin I, Ge P, Brahmachari S, Jhaldiyal A, Kumar M, Andrabi SA, Dawson TM, Dawson VL
Journal of chemical neuroanatomy 2016 Oct;76(Pt B):90-97

Involvement of catecholaminergic neurons in motor innervation of striated muscle in the mouse esophagus.

van der Keylen P, Garreis F, Steigleder R, Sommer D, Neuhuber WL, Wörl J
Histochemistry and cell biology 2016 May;145(5):573-85

Chronic social isolation enhances reproduction in the monogamous prairie vole (Microtus ochrogaster).

Perry AN, Carter CS, Cushing BS
Psychoneuroendocrinology 2016 Jun;68:20-8

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.

Ahuja M, Ammal Kaidery N, Yang L, Calingasan N, Smirnova N, Gaisin A, Gaisina IN, Gazaryan I, Hushpulian DM, Kaddour-Djebbar I, Bollag WB, Morgan JC, Ratan RR, Starkov AA, Beal MF, Thomas B
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jun 8;36(23):6332-51

Thiazine Red(+) platelet inclusions in Cerebral Blood Vessels are first signs in an Alzheimer's Disease mouse model.

Kniewallner KM, Wenzel D, Humpel C
Scientific reports 2016 Jun 27;6:28447

Aggregated single-walled carbon nanotubes attenuate the behavioural and neurochemical effects of methamphetamine in mice.

Xue X, Yang JY, He Y, Wang LR, Liu P, Yu LS, Bi GH, Zhu MM, Liu YY, Xiang RW, Yang XT, Fan XY, Wang XM, Qi J, Zhang HJ, Wei T, Cui W, Ge GL, Xi ZX, Wu CF, Liang XJ
Nature nanotechnology 2016 Jul;11(7):613-20

Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.

Jiang H, Kang SU, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM
eNeuro 2016 Jul-Aug;3(4)

Estrogen protects against dopamine neuron toxicity in primary mesencephalic cultures through an indirect P13K/Akt mediated astrocyte pathway.

Bains M, Roberts JL
Neuroscience letters 2016 Jan 1;610:79-85

HIF2α-arginase axis is essential for the development of pulmonary hypertension.

Cowburn AS, Crosby A, Macias D, Branco C, Colaço RD, Southwood M, Toshner M, Crotty Alexander LE, Morrell NW, Chilvers ER, Johnson RS
Proceedings of the National Academy of Sciences of the United States of America 2016 Aug 2;113(31):8801-6

Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model.

Lin CY, Hsieh HY, Chen CM, Wu SR, Tsai CH, Huang CY, Hua MY, Wei KC, Yeh CK, Liu HL
Journal of controlled release : official journal of the Controlled Release Society 2016 Aug 10;235:72-81

Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration.

Stevens DA, Lee Y, Kang HC, Lee BD, Lee YI, Bower A, Jiang H, Kang SU, Andrabi SA, Dawson VL, Shin JH, Dawson TM
Proceedings of the National Academy of Sciences of the United States of America 2015 Sep 15;112(37):11696-701

Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease.

Liu W, Li Y, Jalewa J, Saunders-Wood T, Li L, Hölscher C
European journal of pharmacology 2015 Oct 15;765:284-90

Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease.

Tsika E, Nguyen AP, Dusonchet J, Colin P, Schneider BL, Moore DJ
Neurobiology of disease 2015 May;77:49-61

PPL2ab neurons restore sexual responses in aged Drosophila males through dopamine.

Kuo SY, Wu CL, Hsieh MY, Lin CT, Wen RK, Chen LC, Chen YH, Yu YW, Wang HD, Su YJ, Lin CJ, Yang CY, Guan HY, Wang PY, Lan TH, Fu TF
Nature communications 2015 Jun 30;6:7490

Li L, Sagot B, Zhou FM
Brain research 2015 Jul 30;1615:12-21

Mitochondrial complex I defects increase ubiquitin in substantia nigra.

Song L, Cortopassi G
Brain research 2015 Jan 12;1594:82-91

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration.

Tsika E, Glauser L, Moser R, Fiser A, Daniel G, Sheerin UM, Lees A, Troncoso JC, Lewis PA, Bandopadhyay R, Schneider BL, Moore DJ
Human molecular genetics 2014 Sep 1;23(17):4621-38

Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration.

Tsika E, Kannan M, Foo CS, Dikeman D, Glauser L, Gellhaar S, Galter D, Knott GW, Dawson TM, Dawson VL, Moore DJ
Neurobiology of disease 2014 Nov;71:345-58

Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue.

Grünewald A, Lax NZ, Rocha MC, Reeve AK, Hepplewhite PD, Rygiel KA, Taylor RW, Turnbull DM
Journal of neuroscience methods 2014 Jul 30;232:143-9

An O2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hypoxia.

Platero-Luengo A, González-Granero S, Durán R, Díaz-Castro B, Piruat JI, García-Verdugo JM, Pardal R, López-Barneo J
Cell 2014 Jan 16;156(1-2):291-303

Age-mediated transcriptomic changes in adult mouse substantia nigra.

Gao L, Hidalgo-Figueroa M, Escudero LM, Díaz-Martín J, López-Barneo J, Pascual A
PloS one 2013;8(4):e62456

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.

Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM
Nature neuroscience 2013 Oct;16(10):1392-400

Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.

Johansson JU, Pradhan S, Lokteva LA, Woodling NS, Ko N, Brown HD, Wang Q, Loh C, Cekanaviciute E, Buckwalter M, Manning-Bog AB, Andreasson KI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Oct 2;33(40):16016-32

Supersensitive presynaptic dopamine D2 receptor inhibition of the striatopallidal projection in nigrostriatal dopamine-deficient mice.

Wei W, Li L, Yu G, Ding S, Li C, Zhou FM
Journal of neurophysiology 2013 Nov;110(9):2203-16

Innervation pattern of the preocular human central retinal artery.

Bergua A, Kapsreiter M, Neuhuber WL, Reitsamer HA, Schrödl F
Experimental eye research 2013 May;110:142-7

Neuroprotective and reparative effects of carotid body grafts in a chronic MPTP model of Parkinson's disease.

Muñoz-Manchado AB, Villadiego J, Suárez-Luna N, Bermejo-Navas A, Garrido-Gil P, Labandeira-García JL, Echevarría M, López-Barneo J, Toledo-Aral JJ
Neurobiology of aging 2013 Mar;34(3):902-15

Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model.

Amschl D, Neddens J, Havas D, Flunkert S, Rabl R, Römer H, Rockenstein E, Masliah E, Windisch M, Hutter-Paier B
BMC neuroscience 2013 Jan 9;14:6

Cellular properties and chemosensory responses of the human carotid body.

Ortega-Sáenz P, Pardal R, Levitsky K, Villadiego J, Muñoz-Manchado AB, Durán R, Bonilla-Henao V, Arias-Mayenco I, Sobrino V, Ordóñez A, Oliver M, Toledo-Aral JJ, López-Barneo J
The Journal of physiology 2013 Dec 15;591(24):6157-73

Severe nigrostriatal degeneration without clinical parkinsonism in patients with polymerase gamma mutations.

Tzoulis C, Tran GT, Schwarzlmüller T, Specht K, Haugarvoll K, Balafkan N, Lilleng PK, Miletic H, Biermann M, Bindoff LA
Brain : a journal of neurology 2013 Aug;136(Pt 8):2393-404

Mesencephalic complex I deficiency does not correlate with parkinsonism in mitochondrial DNA maintenance disorders.

Palin EJ, Paetau A, Suomalainen A
Brain : a journal of neurology 2013 Aug;136(Pt 8):2379-92

PGE2 EP1 receptor deletion attenuates 6-OHDA-induced Parkinsonism in mice: old switch, new target.

Ahmad AS, Maruyama T, Narumiya S, Doré S
Neurotoxicity research 2013 Apr;23(3):260-6

Single dopaminergic neurons that modulate aggression in Drosophila.

Alekseyenko OV, Chan YB, Li R, Kravitz EA
Proceedings of the National Academy of Sciences of the United States of America 2013 Apr 9;110(15):6151-6

Parallel dopamine D1 receptor activity dependence of l-Dopa-induced normal movement and dyskinesia in mice.

Li L, Zhou FM
Neuroscience 2013 Apr 16;236:66-76

Adaptive alternative splicing correlates with less environmental risk of parkinsonism.

Benmoyal-Segal L, Soreq L, Ben-Shaul Y, Ben-Ari S, Ben-Moshe T, Aviel S, Bergman H, Soreq H
Neuro-degenerative diseases 2012;9(2):87-98

Development and characterization of a new Parkinson's disease model resulting from impaired autophagy.

Ahmed I, Liang Y, Schools S, Dawson VL, Dawson TM, Savitt JM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Nov 14;32(46):16503-9

Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2.

Daher JP, Pletnikova O, Biskup S, Musso A, Gellhaar S, Galter D, Troncoso JC, Lee MK, Dawson TM, Dawson VL, Moore DJ
Human molecular genetics 2012 Jun 1;21(11):2420-31

GDNF is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after injury of the nigrostriatal pathway.

Hidalgo-Figueroa M, Bonilla S, Gutiérrez F, Pascual A, López-Barneo J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jan 18;32(3):864-72

Differential impairment of catecholaminergic cell maturation and survival by genetic mitochondrial complex II dysfunction.

Díaz-Castro B, Pintado CO, García-Flores P, López-Barneo J, Piruat JI
Molecular and cellular biology 2012 Aug;32(16):3347-57

Expression of the neuregulin receptor ErbB4 in the brain of the rhesus monkey (Macaca mulatta).

Neddens J, Buonanno A
PloS one 2011;6(11):e27337

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.

Herzig MC, Kolly C, Persohn E, Theil D, Schweizer T, Hafner T, Stemmelen C, Troxler TJ, Schmid P, Danner S, Schnell CR, Mueller M, Kinzel B, Grevot A, Bolognani F, Stirn M, Kuhn RR, Kaupmann K, van der Putten PH, Rovelli G, Shimshek DR
Human molecular genetics 2011 Nov 1;20(21):4209-23

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease.

Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, Troconso JC, Dawson VL, Dawson TM
Cell 2011 Mar 4;144(5):689-702

Brain stem catecholamines circuitry: activation by alcohol and role in the hypothalamic-pituitary-adrenal response to this drug.

Lee S, Craddock Z, Rivier C
Journal of neuroendocrinology 2011 Jun;23(6):531-41

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, Jenkins NA, Copeland NG, Galter D, Thomas B, Lee MK, Dawson TM, Dawson VL, Moore DJ
PloS one 2011 Apr 6;6(4):e18568

Targeted manipulation of serotonergic neurotransmission affects the escalation of aggression in adult male Drosophila melanogaster.

Alekseyenko OV, Lee C, Kravitz EA
PloS one 2010 May 24;5(5):e10806

Effects of IL-6 secreted from astrocytes on the survival of dopaminergic neurons in lipopolysaccharide-induced inflammation.

Li XZ, Bai LM, Yang YP, Luo WF, Hu WD, Chen JP, Mao CJ, Liu CF
Neuroscience research 2009 Nov;65(3):252-8

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease.

Venderova K, Kabbach G, Abdel-Messih E, Zhang Y, Parks RJ, Imai Y, Gehrke S, Ngsee J, Lavoie MJ, Slack RS, Rao Y, Zhang Z, Lu B, Haque ME, Park DS
Human molecular genetics 2009 Nov 15;18(22):4390-404

Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).

Andres-Mateos E, Mejias R, Sasaki M, Li X, Lin BM, Biskup S, Zhang L, Banerjee R, Thomas B, Yang L, Liu G, Beal MF, Huso DL, Dawson TM, Dawson VL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Dec 16;29(50):15846-50

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.

Andres-Mateos E, Perier C, Zhang L, Blanchard-Fillion B, Greco TM, Thomas B, Ko HS, Sasaki M, Ischiropoulos H, Przedborski S, Dawson TM, Dawson VL
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 11;104(37):14807-12

Calcitonin gene-related peptide-evoked sustained tachycardia in calcitonin receptor-like receptor transgenic mice is mediated by sympathetic activity.

Kunz TH, Scott M, Ittner LM, Fischer JA, Born W, Vogel J
American journal of physiology. Heart and circulatory physiology 2007 Oct;293(4):H2155-60

Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.

Ben-Shaul Y, Benmoyal-Segal L, Ben-Ari S, Bergman H, Soreq H
The European journal of neuroscience 2006 Jun;23(11):2915-22

Loss of locus coeruleus neurons and reduced startle in parkin null mice.

Von Coelln R, Thomas B, Savitt JM, Lim KL, Sasaki M, Hess EJ, Dawson VL, Dawson TM
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 20;101(29):10744-9

A hypothalamic-testicular neural pathway is influenced by brain catecholamines, but not testicular blood flow.

Selvage DJ, Lee SY, Parsons LH, Seo DO, Rivier CL
Endocrinology 2004 Apr;145(4):1750-9

Central pathways in the pons and midbrain involved in cardiac sympathoexcitatory reflexes in cats.

Guo Z-, Li P, Longhurst JC
Neuroscience 2002;113(2):435-47

Localization of 5-HT(2A) receptors on dopamine cells in subnuclei of the midbrain A10 cell group.

Nocjar C, Roth BL, Pehek EA
Neuroscience 2002;111(1):163-76

Medullary pathways involved in cardiac sympathoexcitatory reflexes in the cat.

Guo ZL, Lai HC, Longhurst JC
Brain research 2002 Jan 18;925(1):55-66

Superoxide stress identifies neurons at risk in a model of ataxia-telangiectasia.

Quick KL, Dugan LL
Annals of neurology 2001 May;49(5):627-35

Intricate regulation of tyrosine hydroxylase activity and gene expression.

Kumer SC, Vrana KE
Journal of neurochemistry 1996 Aug;67(2):443-62