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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN358211 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Retinoblastoma 1 (RB1) (pSer608) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer608
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Aptamers: prospects in therapeutics and biomedicine.
Dehydroepiandrosterone inhibits the proliferation of human umbilical vein endothelial cells by enhancing the expression of p53 and p21, restricting the phosphorylation of retinoblastoma protein, and is androgen- and estrogen-receptor independent.
Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.
Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma.
Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf.
Yan AC, Bell KM, Breeden MM, Ellington AD
Frontiers in bioscience : a journal and virtual library 2005 May 1;10:1802-27
Frontiers in bioscience : a journal and virtual library 2005 May 1;10:1802-27
Dehydroepiandrosterone inhibits the proliferation of human umbilical vein endothelial cells by enhancing the expression of p53 and p21, restricting the phosphorylation of retinoblastoma protein, and is androgen- and estrogen-receptor independent.
Zapata E, Ventura JL, De la Cruz K, Rodriguez E, Damián P, Massó F, Montaño LF, López-Marure R
The FEBS journal 2005 Mar;272(6):1343-53
The FEBS journal 2005 Mar;272(6):1343-53
Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.
Lieman JH, Worley LA, Harbour JW
The Journal of biological chemistry 2005 Mar 18;280(11):10484-90
The Journal of biological chemistry 2005 Mar 18;280(11):10484-90
Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma.
Roesch A, Becker B, Meyer S, Hafner C, Wild PJ, Landthaler M, Vogt T
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 Apr;18(4):565-72
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 Apr;18(4):565-72
Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf.
Wagner S, Roemer K
Biochemical pharmacology 2005 Apr 1;69(7):1059-67
Biochemical pharmacology 2005 Apr 1;69(7):1059-67
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