Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1881405 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Histone Deacetylase 1 (HDAC1) (C-Term), (AA 421-450) antibody
- Antibody type
- Polyclonal
- Antigen
- This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human HDAC1.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human, Rat
- Host
- Rabbit
- Epitope
- C-Term,AA 421-450
- Antibody clone number
- RB41595
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references SLy2 targets the nuclear SAP30/HDAC1 complex.
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.
Brandt S, Ellwanger K, Beuter-Gunia C, Schuster M, Hausser A, Schmitz I, Beer-Hammer S
The international journal of biochemistry & cell biology 2010 Sep;42(9):1472-81
The international journal of biochemistry & cell biology 2010 Sep;42(9):1472-81
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.
Miller KM, Tjeertes JV, Coates J, Legube G, Polo SE, Britton S, Jackson SP
Nature structural & molecular biology 2010 Sep;17(9):1144-51
Nature structural & molecular biology 2010 Sep;17(9):1144-51
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.
Grausenburger R, Bilic I, Boucheron N, Zupkovitz G, El-Housseiny L, Tschismarov R, Zhang Y, Rembold M, Gaisberger M, Hartl A, Epstein MM, Matthias P, Seiser C, Ellmeier W
Journal of immunology (Baltimore, Md. : 1950) 2010 Sep 15;185(6):3489-97
Journal of immunology (Baltimore, Md. : 1950) 2010 Sep 15;185(6):3489-97
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- HDAC1 Antibody (C-term) (ABIN1881405) western blot analysis in Hela,K562 cell line and rat spleen and testis tissue lysates (35 μg/lane). This demonstrates the HDAC1 antibody detected the HDAC1 protein (arrow).