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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN401285 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-GLI Family Zinc Finger 2 (GLI2) (Isoform alpha), (AA 46-60), (AA 40-60) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to amino acids 46-60 of Human Gli-2 (isoform alpha).
- Description
- Immunoaffinity Chromatography.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Epitope
- Isoform alpha,AA 46-60,AA 40-60
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.1 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Submitted references A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2.
GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter.
The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells.
A new regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1 and cloning of cDNAs encoding its binding proteins.
The GLI gene is a member of the Kruppel family of zinc finger proteins.
The GLI-Kruppel family of human genes.
Roessler E, Ermilov AN, Grange DK, Wang A, Grachtchouk M, Dlugosz AA, Muenke M
Human molecular genetics 2005 Aug 1;14(15):2181-8
Human molecular genetics 2005 Aug 1;14(15):2181-8
GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter.
Ikram MS, Neill GW, Regl G, Eichberger T, Frischauf AM, Aberger F, Quinn A, Philpott M
The Journal of investigative dermatology 2004 Jun;122(6):1503-9
The Journal of investigative dermatology 2004 Jun;122(6):1503-9
The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells.
Regl G, Kasper M, Schnidar H, Eichberger T, Neill GW, Ikram MS, Quinn AG, Philpott MP, Frischauf AM, Aberger F
Oncogene 2004 Feb 12;23(6):1263-74
Oncogene 2004 Feb 12;23(6):1263-74
A new regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1 and cloning of cDNAs encoding its binding proteins.
Tanimura A, Teshima H, Fujisawa J, Yoshida M
Journal of virology 1993 Sep;67(9):5375-82
Journal of virology 1993 Sep;67(9):5375-82
The GLI gene is a member of the Kruppel family of zinc finger proteins.
Kinzler KW, Ruppert JM, Bigner SH, Vogelstein B
Nature 1988 Mar 24;332(6162):371-4
Nature 1988 Mar 24;332(6162):371-4
The GLI-Kruppel family of human genes.
Ruppert JM, Kinzler KW, Wong AJ, Bigner SH, Kao FT, Law ML, Seuanez HN, O'Brien SJ, Vogelstein B
Molecular and cellular biology 1988 Aug;8(8):3104-13
Molecular and cellular biology 1988 Aug;8(8):3104-13
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