ABIN965635

antibody from antibodies-online

Targeting: BAD BBC2, BCL2L8

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965635

Provider

antibodies-online

Product name

anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer112) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human BAD around the phosphorylation site of serine 112 (H-S-SP-Y-P).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer112

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75.

Zhang B, Zhang Y, Shacter E
Molecular and cellular biology 2004 Jul;24(14):6205-14

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Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells.

Rice PL, Washington M, Schleman S, Beard KS, Driggers LJ, Ahnen DJ
Cancer research 2003 Feb 1;63(3):616-20

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Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis.

Wang XQ, Sun P, Paller AS
The Journal of biological chemistry 2001 Nov 30;276(48):44504-11