ABIN967293

antibody from antibodies-online

Targeting: DFFB CAD, CPAN, DFF-40, DFF40

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN967293

Provider

antibodies-online

Product name

anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (AA 203-218) antibody

Antibody type

Polyclonal

Antigen

Human DFF40 peptide

Reactivity

Human

Host

Rabbit

Vial size

50 µg

Concentration

0.5 mg/ml

Storage

Store undiluted at 4°C.

References

Submitted references

Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1.

Liu X, Zou H, Widlak P, Garrard W, Wang X
The Journal of biological chemistry 1999 May 14;274(20):13836-40

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The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.

Liu X, Li P, Widlak P, Zou H, Luo X, Garrard WT, Wang X
Proceedings of the National Academy of Sciences of the United States of America 1998 Jul 21;95(15):8461-6

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.

Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S
Nature 1998 Jan 1;391(6662):43-50

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Molecular cloning and characterization of human caspase-activated DNase.

Mukae N, Enari M, Sakahira H, Fukuda Y, Inazawa J, Toh H, Nagata S
Proceedings of the National Academy of Sciences of the United States of America 1998 Aug 4;95(16):9123-8