MAB6732-100

antibody from Novus Biologicals

Targeting: IFNGR1 CD119, IFNGR

Blocking/Neutralizing (Supportive data in Antibodypedia)

Antibody Data

Product number

MAB6732-100

Provider

Novus Biologicals

Product name

Mouse Monoclonal IFN-gamma R1/CD119 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human IFN-gamma R1/CD119 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse IFN-gamma R1, recombinant human (rh) IFN-gamma R2, or rhIL-10 R beta is observed.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

100 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Blocking/Neutralizing

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

IFN-gamma Inhibition of EMCV-induced Cytopathy and Neutralization by Human IFN-gamma R1/CD119 Antibody. Recombinant Human IFN-gamma (Catalog # 285-IF) reduces the Encephalomyocarditis Virus (EMCV)-induced cytopathy in the HeLa human cervical epithelial carcinoma cell line in a dose-dependent manner (orange line). Inhibition of EMCV activity elicited by Recombinant Human IFN-gamma (2 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human IFN-gamma R1/CD119 Mono-clonal Antibody (Catalog # MAB6732). The ND₅₀ is typically 0.03-0.15 µg/mL.