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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB200F - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal IL-1 alpha/IL-1F1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human IL-1 alpha/IL-1F1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse IL-1 alpha , recombinant rat IL-1 alpha , recombinant cotton rat IL-1 alpha , recombinant human (rh) IL-1 beta or rhIL-18 is observed.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 50 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence.
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
IL-34- and M-CSF-induced macrophages switch memory T cells into Th17 cells via membrane IL-1α.
Ong SM, Hadadi E, Dang TM, Yeap WH, Tan CT, Ng TP, Larbi A, Wong SC
Cell death & disease 2018 Feb 15;9(3):266
Cell death & disease 2018 Feb 15;9(3):266
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, Zhou L, Curran SC, Davalos AR, Wilson-Edell KA, Liu S, Limbad C, Demaria M, Li P, Hubbard GB, Ikeno Y, Javors M, Desprez PY, Benz CC, Kapahi P, Nelson PS, Campisi J
Nature cell biology 2015 Aug;17(8):1049-61
Nature cell biology 2015 Aug;17(8):1049-61
IL-34- and M-CSF-induced macrophages switch memory T cells into Th17 cells via membrane IL-1α.
Foucher ED, Blanchard S, Preisser L, Descamps P, Ifrah N, Delneste Y, Jeannin P
European journal of immunology 2015 Apr;45(4):1092-102
European journal of immunology 2015 Apr;45(4):1092-102
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of IL-1 alpha/IL-1F1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) treated with LPS for 24 hours were stained with Mouse Anti-Human IL-1 alpha/IL-1F1 Membrane Form Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB200F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.
