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Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- AB-400-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-1 alpha/IL-1F1 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A or G purified. Detects IL-1 alpha/IL-1F1 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant rat IL-1 alpha is observed and less than 2% cross-reactivity with recombinant human (rh) IL-1 alpha is observed. Neutralizes the biological activity of recombinant mouse (rm) IL-1 alpha , but will not neutralize the biological activity of rhIL-1 alpha , rhIL-1 beta , or rmIL-1 beta .
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 1 mg
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism.
Cutting Edge: A Natural Antisense Transcript, AS-IL1α, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1α.
Intravenous human interleukin-1alpha impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum.
Zhao C, Zhang W, Zhao Y, Yang Y, Luo H, Ji G, Dong E, Deng H, Lin S, Wei Y, Yang H
Scientific reports 2016 Jan 14;6:19404
Scientific reports 2016 Jan 14;6:19404
Cutting Edge: A Natural Antisense Transcript, AS-IL1α, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1α.
Chan J, Atianand M, Jiang Z, Carpenter S, Aiello D, Elling R, Fitzgerald KA, Caffrey DR
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1359-63
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1359-63
Intravenous human interleukin-1alpha impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum.
Banks WA, Farr SA, La Scola ME, Morley JE
The Journal of pharmacology and experimental therapeutics 2001 Nov;299(2):536-41
The Journal of pharmacology and experimental therapeutics 2001 Nov;299(2):536-41
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Cell Proliferation Induced by IL-1a/IL-1F1 and Neutral-ization by Mouse IL-1a/IL-1F1 Antibody. Cell Proliferation Induced by IL-1a/IL-1F1 and Neutral-ization by Mouse IL-1a/IL-1F1 Antibody.
