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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN358374 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183) antibody
- Antibody type
- Polyclonal
- Description
- Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pThr183
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation.
A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase.
c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production.
c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells.
Luo W, Ng WW, Jin LH, Ye Z, Han J, Lin SC
The Journal of biological chemistry 2003 Sep 26;278(39):37451-8
The Journal of biological chemistry 2003 Sep 26;278(39):37451-8
A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
Deng Y, Ren X, Yang L, Lin Y, Wu X
Cell 2003 Oct 3;115(1):61-70
Cell 2003 Oct 3;115(1):61-70
Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase.
Ghosh J
Biochemical and biophysical research communications 2003 Jul 25;307(2):342-9
Biochemical and biophysical research communications 2003 Jul 25;307(2):342-9
c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production.
Utsugi M, Dobashi K, Ishizuka T, Endou K, Hamuro J, Murata Y, Nakazawa T, Mori M
Journal of immunology (Baltimore, Md. : 1950) 2003 Jul 15;171(2):628-35
Journal of immunology (Baltimore, Md. : 1950) 2003 Jul 15;171(2):628-35
c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells.
Vivo C, Liu W, Broaddus VC
The Journal of biological chemistry 2003 Jul 11;278(28):25461-7
The Journal of biological chemistry 2003 Jul 11;278(28):25461-7
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