ABIN967918

antibody from antibodies-online

Targeting: NCF1 NCF1A, NOXO2, p47phox, SH3PXD1A

Western blot (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN967918

Provider

antibodies-online

Product name

anti-Neutrophil Cytosolic Factor 1 (NCF1) (AA 18-197) antibody

Antibody type

Monoclonal

Antigen

Human p47[phox]

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

1

Vial size

50 µg

Concentration

250 µg/ml

Storage

Store undiluted at -20° C.

References

Submitted references

Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase.

Shiose A, Sumimoto H
The Journal of biological chemistry 2000 May 5;275(18):13793-801

---

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating the oxidase.

Ago T, Nunoi H, Ito T, Sumimoto H
The Journal of biological chemistry 1999 Nov 19;274(47):33644-53

---

Anionic amphiphile-independent activation of the phagocyte NADPH oxidase in a cell-free system by p47phox and p67phox, both in C terminally truncated forms. Implication for regulatory Src homology 3 domain-mediated interactions.

Hata K, Ito T, Takeshige K, Sumimoto H
The Journal of biological chemistry 1998 Feb 13;273(7):4232-6

---

Cloning and functional expression of the mouse homologue of p47phox.

Jackson SH, Malech HL, Kozak CA, Lomax KJ, Gallin JI, Holland SM
Immunogenetics 1994;39(4):272-5

---

The respiratory burst oxidase.

Chanock SJ, el Benna J, Smith RM, Babior BM
The Journal of biological chemistry 1994 Oct 7;269(40):24519-22