ABIN362422

antibody from antibodies-online

Targeting: NTRK1 MTC, TRK, TRKA

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362422

Provider

antibodies-online

Product name

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (pTyr791) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pTyr791 (P-V-Y (p) -L-D) derived from Human TrkA. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human

Host

Rabbit

Epitope

pTyr791

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB.

Wiese S, Jablonka S, Holtmann B, Orel N, Rajagopal R, Chao MV, Sendtner M
Proceedings of the National Academy of Sciences of the United States of America 2007 Oct 23;104(43):17210-5

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Trk-signaling endosomes are generated by Rac-dependent macroendocytosis.

Valdez G, Philippidou P, Rosenbaum J, Akmentin W, Shao Y, Halegoua S
Proceedings of the National Academy of Sciences of the United States of America 2007 Jul 24;104(30):12270-5

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The transcription factor Runx3 represses the neurotrophin receptor TrkB during lineage commitment of dorsal root ganglion neurons.

Inoue K, Ito K, Osato M, Lee B, Bae SC, Ito Y
The Journal of biological chemistry 2007 Aug 17;282(33):24175-84