519106

antibody from BioLegend
Targeting: IL16 FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16
Provider product page for 519106

Antibody data

Product number
519106 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#519106, RRID:AB_10897940
Product name
PE anti-human IL-16
Antibody type
Monoclonal
Antigen
Peptide corresponding to amino acids 615 to 630 (RRKSLQSKETTAAGDS) of IL-16
Description
Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (pro-IL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but its biologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4+ T cells, monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, and also inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminal repeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelial cells, and fibroblasts. CD4 and CD9 are the receptors of IL-16.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
IL16 protein structure - 519106 shown in red.