NBP2-34507AF647

antibody from Novus Biologicals
Targeting: ITGB4 CD104
Provider product page for NBP2-34507AF647
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-34507AF647 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Integrin beta 4/CD104 Antibody
Antibody type
Monoclonal
Description
Protein A purified. Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C in the dark.
ITGB4 protein structure - NBP2-34507AF647 shown in red.